Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Ccel_3361KEGG: cth:Cthe_2166 putative PAS/PAC sensor protein; TIGRFAM: PAS sensor protein; PFAM: Stage II sporulation E family protein; SMART: protein phosphatase 2C domain protein. (373 aa)    
Predicted Functional Partners:
Ccel_0398
Anti-sigma-factor antagonist; TIGRFAM: anti-anti-sigma factor; PFAM: Sulfate transporter/antisigma-factor antagonist STAS; KEGG: cth:Cthe_2898 anti-sigma-factor antagonist.
 
 
 0.975
Ccel_0399
KEGG: cth:Cthe_2899 putative anti-sigma regulatory factor, serine/threonine protein kinase.
 
 
 0.939
Ccel_0401
KEGG: cth:Cthe_2901 putative anti-sigma regulatory factor, serine/threonine protein kinase.
 
 
 0.929
Ccel_3099
KEGG: cth:Cthe_2622 hypothetical protein.
  
    0.918
Ccel_3104
PFAM: Radical SAM domain protein; biotin and thiamin synthesis associated; KEGG: cbe:Cbei_4439 thiamine biosynthesis protein ThiH.
   
    0.835
Ccel_2039
PFAM: surface presentation of antigens (SPOA) protein; flagellar motor switch protein FliM; KEGG: cth:Cthe_0477 flagellar motor switch protein FliM.
  
    0.809
Ccel_0400
TIGRFAM: RNA polymerase sigma factor, sigma-70 family; RNA polymerase sigma-70 factor, sigma-B/F/G subfamily; PFAM: sigma-70 region 3 domain protein; sigma-70 region 2 domain protein; sigma-70 region 4 domain protein; KEGG: cth:Cthe_2900 RNA polymerase, sigma 28 subunit.
 
 
 0.787
spoIIAB
Anti-sigma regulatory factor, serine/threonine protein kinase; Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti- anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition.
  
 
 0.780
Ccel_0626
TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; EAL domain protein; KEGG: wsu:WS2095 hypothetical protein.
  
    0.719
Ccel_2049
PFAM: flagellar assembly protein FliH; KEGG: cth:Cthe_0467 flagellar biosynthesis/type III secretory pathway protein-like protein.
 
    0.693
Your Current Organism:
Ruminiclostridium cellulolyticum
NCBI taxonomy Id: 394503
Other names: Clostridium cellulolyticum H10, R. cellulolyticum H10, Ruminiclostridium cellulolyticum H10
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