| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| Ccel_0132 | Ccel_2430 | Ccel_0132 | Ccel_2430 | TIGRFAM: cyanophycin synthetase; PFAM: phosphoribosylglycinamide synthetase; cytoplasmic peptidoglycan synthetase domain protein; Mur ligase middle domain protein; RimK domain protein ATP-grasp; KEGG: cth:Cthe_2204 cyanophycin synthetase. | PFAM: Glu/Leu/Phe/Val dehydrogenase; Glu/Leu/Phe/Val dehydrogenase dimerisation region; KEGG: cth:Cthe_0374 glutamate dehydrogenase; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. | 0.415 |
| Ccel_0132 | murC | Ccel_0132 | Ccel_3096 | TIGRFAM: cyanophycin synthetase; PFAM: phosphoribosylglycinamide synthetase; cytoplasmic peptidoglycan synthetase domain protein; Mur ligase middle domain protein; RimK domain protein ATP-grasp; KEGG: cth:Cthe_2204 cyanophycin synthetase. | UDP-N-acetylmuramate/alanine ligase; Cell wall formation; Belongs to the MurCDEF family. | 0.903 |
| Ccel_0132 | murD | Ccel_0132 | Ccel_1726 | TIGRFAM: cyanophycin synthetase; PFAM: phosphoribosylglycinamide synthetase; cytoplasmic peptidoglycan synthetase domain protein; Mur ligase middle domain protein; RimK domain protein ATP-grasp; KEGG: cth:Cthe_2204 cyanophycin synthetase. | UDP-N-acetylmuramoylalanine/D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family. | 0.930 |
| Ccel_0132 | murI | Ccel_0132 | Ccel_3402 | TIGRFAM: cyanophycin synthetase; PFAM: phosphoribosylglycinamide synthetase; cytoplasmic peptidoglycan synthetase domain protein; Mur ligase middle domain protein; RimK domain protein ATP-grasp; KEGG: cth:Cthe_2204 cyanophycin synthetase. | Glutamate racemase; Provides the (R)-glutamate required for cell wall biosynthesis. | 0.598 |
| Ccel_0561 | Ccel_0981 | Ccel_0561 | Ccel_0981 | PFAM: glutamine synthetase catalytic region; KEGG: tpd:Teth39_1666 glutamine synthetase, catalytic region. | PFAM: Pyridoxal-dependent decarboxylase; KEGG: spc:Sputcn32_1469 pyridoxal-dependent decarboxylase. | 0.900 |
| Ccel_0561 | Ccel_2430 | Ccel_0561 | Ccel_2430 | PFAM: glutamine synthetase catalytic region; KEGG: tpd:Teth39_1666 glutamine synthetase, catalytic region. | PFAM: Glu/Leu/Phe/Val dehydrogenase; Glu/Leu/Phe/Val dehydrogenase dimerisation region; KEGG: cth:Cthe_0374 glutamate dehydrogenase; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. | 0.917 |
| Ccel_0561 | Ccel_2545 | Ccel_0561 | Ccel_2545 | PFAM: glutamine synthetase catalytic region; KEGG: tpd:Teth39_1666 glutamine synthetase, catalytic region. | TIGRFAM: glutamate synthase (NADPH), homotetrameric; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; KEGG: cth:Cthe_0372 sulfide dehydrogenase (flavoprotein) subunit SudA. | 0.914 |
| Ccel_0561 | murI | Ccel_0561 | Ccel_3402 | PFAM: glutamine synthetase catalytic region; KEGG: tpd:Teth39_1666 glutamine synthetase, catalytic region. | Glutamate racemase; Provides the (R)-glutamate required for cell wall biosynthesis. | 0.813 |
| Ccel_0981 | Ccel_0561 | Ccel_0981 | Ccel_0561 | PFAM: Pyridoxal-dependent decarboxylase; KEGG: spc:Sputcn32_1469 pyridoxal-dependent decarboxylase. | PFAM: glutamine synthetase catalytic region; KEGG: tpd:Teth39_1666 glutamine synthetase, catalytic region. | 0.900 |
| Ccel_0981 | Ccel_2430 | Ccel_0981 | Ccel_2430 | PFAM: Pyridoxal-dependent decarboxylase; KEGG: spc:Sputcn32_1469 pyridoxal-dependent decarboxylase. | PFAM: Glu/Leu/Phe/Val dehydrogenase; Glu/Leu/Phe/Val dehydrogenase dimerisation region; KEGG: cth:Cthe_0374 glutamate dehydrogenase; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. | 0.913 |
| Ccel_0981 | Ccel_2545 | Ccel_0981 | Ccel_2545 | PFAM: Pyridoxal-dependent decarboxylase; KEGG: spc:Sputcn32_1469 pyridoxal-dependent decarboxylase. | TIGRFAM: glutamate synthase (NADPH), homotetrameric; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; KEGG: cth:Cthe_0372 sulfide dehydrogenase (flavoprotein) subunit SudA. | 0.900 |
| Ccel_0981 | murI | Ccel_0981 | Ccel_3402 | PFAM: Pyridoxal-dependent decarboxylase; KEGG: spc:Sputcn32_1469 pyridoxal-dependent decarboxylase. | Glutamate racemase; Provides the (R)-glutamate required for cell wall biosynthesis. | 0.800 |
| Ccel_1353 | murI | Ccel_1353 | Ccel_3402 | Non-canonical purine NTP pyrophosphatase, rdgB/HAM1 family; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | Glutamate racemase; Provides the (R)-glutamate required for cell wall biosynthesis. | 0.921 |
| Ccel_2430 | Ccel_0132 | Ccel_2430 | Ccel_0132 | PFAM: Glu/Leu/Phe/Val dehydrogenase; Glu/Leu/Phe/Val dehydrogenase dimerisation region; KEGG: cth:Cthe_0374 glutamate dehydrogenase; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. | TIGRFAM: cyanophycin synthetase; PFAM: phosphoribosylglycinamide synthetase; cytoplasmic peptidoglycan synthetase domain protein; Mur ligase middle domain protein; RimK domain protein ATP-grasp; KEGG: cth:Cthe_2204 cyanophycin synthetase. | 0.415 |
| Ccel_2430 | Ccel_0561 | Ccel_2430 | Ccel_0561 | PFAM: Glu/Leu/Phe/Val dehydrogenase; Glu/Leu/Phe/Val dehydrogenase dimerisation region; KEGG: cth:Cthe_0374 glutamate dehydrogenase; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. | PFAM: glutamine synthetase catalytic region; KEGG: tpd:Teth39_1666 glutamine synthetase, catalytic region. | 0.917 |
| Ccel_2430 | Ccel_0981 | Ccel_2430 | Ccel_0981 | PFAM: Glu/Leu/Phe/Val dehydrogenase; Glu/Leu/Phe/Val dehydrogenase dimerisation region; KEGG: cth:Cthe_0374 glutamate dehydrogenase; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. | PFAM: Pyridoxal-dependent decarboxylase; KEGG: spc:Sputcn32_1469 pyridoxal-dependent decarboxylase. | 0.913 |
| Ccel_2430 | Ccel_2545 | Ccel_2430 | Ccel_2545 | PFAM: Glu/Leu/Phe/Val dehydrogenase; Glu/Leu/Phe/Val dehydrogenase dimerisation region; KEGG: cth:Cthe_0374 glutamate dehydrogenase; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. | TIGRFAM: glutamate synthase (NADPH), homotetrameric; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; KEGG: cth:Cthe_0372 sulfide dehydrogenase (flavoprotein) subunit SudA. | 0.942 |
| Ccel_2430 | murI | Ccel_2430 | Ccel_3402 | PFAM: Glu/Leu/Phe/Val dehydrogenase; Glu/Leu/Phe/Val dehydrogenase dimerisation region; KEGG: cth:Cthe_0374 glutamate dehydrogenase; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. | Glutamate racemase; Provides the (R)-glutamate required for cell wall biosynthesis. | 0.846 |
| Ccel_2545 | Ccel_0561 | Ccel_2545 | Ccel_0561 | TIGRFAM: glutamate synthase (NADPH), homotetrameric; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; KEGG: cth:Cthe_0372 sulfide dehydrogenase (flavoprotein) subunit SudA. | PFAM: glutamine synthetase catalytic region; KEGG: tpd:Teth39_1666 glutamine synthetase, catalytic region. | 0.914 |
| Ccel_2545 | Ccel_0981 | Ccel_2545 | Ccel_0981 | TIGRFAM: glutamate synthase (NADPH), homotetrameric; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; KEGG: cth:Cthe_0372 sulfide dehydrogenase (flavoprotein) subunit SudA. | PFAM: Pyridoxal-dependent decarboxylase; KEGG: spc:Sputcn32_1469 pyridoxal-dependent decarboxylase. | 0.900 |