Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Ccel_3405PFAM: PP-loop domain protein; KEGG: cth:Cthe_2181 ATPase; Belongs to the TtcA family. (239 aa)    
Predicted Functional Partners:
Ccel_0923
PFAM: ExsB family protein; KEGG: cth:Cthe_1841 hypothetical protein.
 
    0.618
Ccel_3406
KEGG: cth:Cthe_2182 Ig-like, group 2.
       0.542
pth
peptidyl-tRNA hydrolase; The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis. Belongs to the PTH family.
  
  
 0.495
mfd
Transcription-repair coupling factor; Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site; In the C-terminal section; belongs to the helicase family. RecG subfamily.
  
    0.467
Ccel_2331
TIGRFAM: amino acid adenylation domain protein; PFAM: AMP-dependent synthetase and ligase; condensation domain protein; short-chain dehydrogenase/reductase SDR; phosphopantetheine-binding; KR domain protein; Beta-ketoacyl synthase; KEGG: bsu:BSU17180 polyketide synthase of type I.
  
 
 0.452
Ccel_0262
PFAM: glycosyl transferase family 4; UDP-N-acetylglucosamine 2-epimerase; KEGG: cth:Cthe_2601 UDP-N-acetylglucosamine 2-epimerase.
  
  
 0.446
Ccel_2378
TIGRFAM: amino acid adenylation domain protein; PFAM: AMP-dependent synthetase and ligase; condensation domain protein; short-chain dehydrogenase/reductase SDR; phosphopantetheine-binding; KR domain protein; Beta-ketoacyl synthase; KEGG: bld:BLi00401 lichenysin synthetase A.
  
   0.437
Ccel_0688
PFAM: Radical SAM domain protein; SMART: Elongator protein 3/MiaB/NifB; KEGG: cth:Cthe_0930 radical SAM family protein.
   
 
 0.409
Ccel_1144
PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; SirA family protein; Rhodanese domain protein; pyridine nucleotide-disulphide oxidoreductase dimerisation region; KEGG: afl:Aflv_0303 multidomain redox protein (NAD(FAD)-dependent oxidoreductase; rhodanese domain; SirA-like redox domain; peroxiredoxin domain); Belongs to the sulfur carrier protein TusA family.
     
 0.401
Your Current Organism:
Ruminiclostridium cellulolyticum
NCBI taxonomy Id: 394503
Other names: Clostridium cellulolyticum H10, R. cellulolyticum H10, Ruminiclostridium cellulolyticum H10
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