Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Ccel_3447PFAM: peptidase S8 and S53 subtilisin kexin sedolisin; KEGG: cbf:CLI_3230 S8/S53 family peptidase. (396 aa)    
Predicted Functional Partners:
Ccel_2369
KEGG: cbf:CLI_3233 hypothetical protein.
 
     0.648
Ccel_3448
PFAM: NAD-dependent epimerase/dehydratase; dTDP-4-dehydrorhamnose reductase; Male sterility domain; KEGG: pfu:PF1357 UDP-or dTTP-glucose 4-epimerase or 4-6-dehydratase.
  
    0.546
Ccel_3449
PFAM: Transketolase central region; Transketolase domain protein; KEGG: rpb:RPB_3807 acetoin dehydrogenase (TPP-dependent) beta chain.
     
 0.517
Ccel_3445
KEGG: gbm:Gbem_3741 TPR repeat-containing protein.
  
    0.514
Ccel_3444
Hypothetical protein; KEGG: gbm:Gbem_3741 TPR repeat-containing protein.
       0.509
Ccel_3446
KEGG: gbm:Gbem_3741 TPR repeat-containing protein.
       0.509
Ccel_2893
Chitinase II; SMART: leucine-rich repeat-containing protein typical subtype; chitinase II; KEGG: cpy:Cphy_1815 leucine-rich repeat-containing protein.
 
 
 0.462
Ccel_3450
PFAM: dehydrogenase E1 component; KEGG: tpd:Teth39_0790 pyruvate dehydrogenase (acetyl-transferring).
       0.438
Ccel_2520
PFAM: protein of unknown function DUF990; KEGG: cpy:Cphy_0980 hypothetical protein.
  
     0.434
Ccel_3349
KEGG: ckl:CKL_2427 hypothetical protein.
  
 
 0.415
Your Current Organism:
Ruminiclostridium cellulolyticum
NCBI taxonomy Id: 394503
Other names: Clostridium cellulolyticum H10, R. cellulolyticum H10, Ruminiclostridium cellulolyticum H10
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