Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Ccel_3450PFAM: dehydrogenase E1 component; KEGG: tpd:Teth39_0790 pyruvate dehydrogenase (acetyl-transferring). (321 aa)    
Predicted Functional Partners:
Ccel_3449
PFAM: Transketolase central region; Transketolase domain protein; KEGG: rpb:RPB_3807 acetoin dehydrogenase (TPP-dependent) beta chain.
 0.999
Ccel_0950
HI0933 family protein; PFAM: glucose-inhibited division protein A; HI0933 family protein; FAD dependent oxidoreductase; KEGG: tbd:Tbd_1475 hypothetical protein.
  
 
 0.857
Ccel_2430
PFAM: Glu/Leu/Phe/Val dehydrogenase; Glu/Leu/Phe/Val dehydrogenase dimerisation region; KEGG: cth:Cthe_0374 glutamate dehydrogenase; Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
  
  
 0.648
Ccel_3451
KEGG: gbm:Gbem_3741 TPR repeat-containing protein.
       0.648
Ccel_3448
PFAM: NAD-dependent epimerase/dehydratase; dTDP-4-dehydrorhamnose reductase; Male sterility domain; KEGG: pfu:PF1357 UDP-or dTTP-glucose 4-epimerase or 4-6-dehydratase.
     
 0.635
Ccel_3452
PFAM: Nucleotidyl transferase; KEGG: csc:Csac_2018 mannose-1-phosphate guanylyltransferase (GDP).
     
 0.598
Ccel_2137
TIGRFAM: phosphate acetyltransferase; PFAM: phosphate acetyl/butaryl transferase; KEGG: cth:Cthe_1029 phosphotransacetylase.
  
  
 0.567
Ccel_0016
PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; pyruvate ferredoxin/flavodoxin oxidoreductase; pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; 4Fe-4S ferredoxin, iron-sulphur binding, conserved site; KEGG: cpy:Cphy_3558 pyruvate flavodoxin/ferredoxin oxidoreductase domain-containing protein.
     
 0.560
Ccel_2331
TIGRFAM: amino acid adenylation domain protein; PFAM: AMP-dependent synthetase and ligase; condensation domain protein; short-chain dehydrogenase/reductase SDR; phosphopantetheine-binding; KR domain protein; Beta-ketoacyl synthase; KEGG: bsu:BSU17180 polyketide synthase of type I.
  
 
 0.533
Ccel_1164
PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; pyruvate ferredoxin/flavodoxin oxidoreductase; pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; 4Fe-4S ferredoxin, iron-sulphur binding, conserved site; KEGG: cdf:CD2682 pyruvate-flavodoxin oxidoreductase.
     
 0.518
Your Current Organism:
Ruminiclostridium cellulolyticum
NCBI taxonomy Id: 394503
Other names: Clostridium cellulolyticum H10, R. cellulolyticum H10, Ruminiclostridium cellulolyticum H10
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