STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
cobSCobalamin synthase; Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'- phosphate; Belongs to the CobS family. (248 aa)    
Predicted Functional Partners:
cobU
Bifunctional adenosylcobalamin biosynthesis protein CobU.
 
 
 0.993
cobQ
Cobyric acid synthase; Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily.
 
  
 0.985
cbiB
Cobalamin biosynthesis protein CbiB; Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group.
 
   
 0.968
cbiH
cobalt-precorrin-3B C(17)-methyltransferase.
 
  
 0.955
cobO
Cob(I)yrinic acid a,c-diamide adenosyltransferase.
 
 
 0.936
cobC
Alpha-ribazole phosphatase; Belongs to the phosphoglycerate mutase family.
 
 
 0.923
cobT
Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase; Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB).
 
  
 0.913
EUAN_00820
Hypothetical protein; NfeD-like C-terminal, partner-binding.
   
    0.881
cobD
Threonine-phosphate decarboxylase.
 
   
 0.866
cbiF
Cobalt-precorrin-4 C(11)-methyltransferase; Belongs to the precorrin methyltransferase family.
 
 
 0.856
Your Current Organism:
Andreesenia angusta
NCBI taxonomy Id: 39480
Other names: A. angusta, ATCC 43737, Eubacterium angustum, strain MK-1
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