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Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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nnr_2Bifunctional NAD(P)H-hydrate repair enzyme Nnr; Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX; Belongs to the NnrE/AIBP family. (228 aa)    
Predicted Functional Partners:
nnr_1
Bifunctional NAD(P)H-hydrate repair enzyme Nnr; Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S-and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Belongs to the NnrD/CARKD family.
  
 0.984
hndC_2
NADP-reducing hydrogenase subunit HndC.
  
   0.898
cshA_1
DEAD-box ATP-dependent RNA helicase CshA.
  
 0.814
dbpA
ATP-dependent RNA helicase DbpA; Belongs to the DEAD box helicase family.
  
 0.814
cshA_2
DEAD-box ATP-dependent RNA helicase CshA; Belongs to the DEAD box helicase family.
  
 0.814
rhlE
ATP-dependent RNA helicase RhlE.
  
 0.814
tsaE
tRNA threonylcarbamoyladenosine biosynthesis protein TsaE.
  
 
 0.803
groL
60 kDa chaperonin; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions.
  
   0.788
EUAN_20230
30S ribosomal protein S1 homolog.
   
   0.696
glgP
Glycogen phosphorylase; Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.
  
   0.678
Your Current Organism:
Andreesenia angusta
NCBI taxonomy Id: 39480
Other names: A. angusta, ATCC 43737, Eubacterium angustum, strain MK-1
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