| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| EUAN_20230 | nnr_2 | EUAN_20230 | EUAN_19770 | 30S ribosomal protein S1 homolog. | Bifunctional NAD(P)H-hydrate repair enzyme Nnr; Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX; Belongs to the NnrE/AIBP family. | 0.696 |
| EUAN_20230 | tsaE | EUAN_20230 | EUAN_20260 | 30S ribosomal protein S1 homolog. | tRNA threonylcarbamoyladenosine biosynthesis protein TsaE. | 0.772 |
| cshA_1 | cshA_2 | EUAN_01260 | EUAN_05240 | DEAD-box ATP-dependent RNA helicase CshA. | DEAD-box ATP-dependent RNA helicase CshA; Belongs to the DEAD box helicase family. | 0.492 |
| cshA_1 | nnr_2 | EUAN_01260 | EUAN_19770 | DEAD-box ATP-dependent RNA helicase CshA. | Bifunctional NAD(P)H-hydrate repair enzyme Nnr; Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX; Belongs to the NnrE/AIBP family. | 0.814 |
| cshA_1 | rhlE | EUAN_01260 | EUAN_06480 | DEAD-box ATP-dependent RNA helicase CshA. | ATP-dependent RNA helicase RhlE. | 0.492 |
| cshA_2 | cshA_1 | EUAN_05240 | EUAN_01260 | DEAD-box ATP-dependent RNA helicase CshA; Belongs to the DEAD box helicase family. | DEAD-box ATP-dependent RNA helicase CshA. | 0.492 |
| cshA_2 | nnr_2 | EUAN_05240 | EUAN_19770 | DEAD-box ATP-dependent RNA helicase CshA; Belongs to the DEAD box helicase family. | Bifunctional NAD(P)H-hydrate repair enzyme Nnr; Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX; Belongs to the NnrE/AIBP family. | 0.814 |
| dbpA | nnr_2 | EUAN_01590 | EUAN_19770 | ATP-dependent RNA helicase DbpA; Belongs to the DEAD box helicase family. | Bifunctional NAD(P)H-hydrate repair enzyme Nnr; Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX; Belongs to the NnrE/AIBP family. | 0.814 |
| glgP | nnr_2 | EUAN_02940 | EUAN_19770 | Glycogen phosphorylase; Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties. | Bifunctional NAD(P)H-hydrate repair enzyme Nnr; Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX; Belongs to the NnrE/AIBP family. | 0.678 |
| groL | hndC_2 | EUAN_20460 | EUAN_22800 | 60 kDa chaperonin; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. | NADP-reducing hydrogenase subunit HndC. | 0.501 |
| groL | nnr_1 | EUAN_20460 | EUAN_15300 | 60 kDa chaperonin; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. | Bifunctional NAD(P)H-hydrate repair enzyme Nnr; Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S-and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Belongs to the NnrD/CARKD family. | 0.558 |
| groL | nnr_2 | EUAN_20460 | EUAN_19770 | 60 kDa chaperonin; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. | Bifunctional NAD(P)H-hydrate repair enzyme Nnr; Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX; Belongs to the NnrE/AIBP family. | 0.788 |
| hndC_2 | groL | EUAN_22800 | EUAN_20460 | NADP-reducing hydrogenase subunit HndC. | 60 kDa chaperonin; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. | 0.501 |
| hndC_2 | nnr_2 | EUAN_22800 | EUAN_19770 | NADP-reducing hydrogenase subunit HndC. | Bifunctional NAD(P)H-hydrate repair enzyme Nnr; Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX; Belongs to the NnrE/AIBP family. | 0.898 |
| nnr_1 | groL | EUAN_15300 | EUAN_20460 | Bifunctional NAD(P)H-hydrate repair enzyme Nnr; Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S-and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Belongs to the NnrD/CARKD family. | 60 kDa chaperonin; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. | 0.558 |
| nnr_1 | nnr_2 | EUAN_15300 | EUAN_19770 | Bifunctional NAD(P)H-hydrate repair enzyme Nnr; Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S-and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Belongs to the NnrD/CARKD family. | Bifunctional NAD(P)H-hydrate repair enzyme Nnr; Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX; Belongs to the NnrE/AIBP family. | 0.984 |
| nnr_1 | tsaE | EUAN_15300 | EUAN_20260 | Bifunctional NAD(P)H-hydrate repair enzyme Nnr; Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S-and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Belongs to the NnrD/CARKD family. | tRNA threonylcarbamoyladenosine biosynthesis protein TsaE. | 0.470 |
| nnr_2 | EUAN_20230 | EUAN_19770 | EUAN_20230 | Bifunctional NAD(P)H-hydrate repair enzyme Nnr; Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX; Belongs to the NnrE/AIBP family. | 30S ribosomal protein S1 homolog. | 0.696 |
| nnr_2 | cshA_1 | EUAN_19770 | EUAN_01260 | Bifunctional NAD(P)H-hydrate repair enzyme Nnr; Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX; Belongs to the NnrE/AIBP family. | DEAD-box ATP-dependent RNA helicase CshA. | 0.814 |
| nnr_2 | cshA_2 | EUAN_19770 | EUAN_05240 | Bifunctional NAD(P)H-hydrate repair enzyme Nnr; Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX; Belongs to the NnrE/AIBP family. | DEAD-box ATP-dependent RNA helicase CshA; Belongs to the DEAD box helicase family. | 0.814 |