CUP41553.1 protein (Faecalicatena contorta) - STRING interaction network

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

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Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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co-expression

protein homology

Your Input:

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Coexpression

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[Homology]

Score

CUP41553.1

Type IV secretory pathway%2C VirB4 components. (818 aa)

Predicted Functional Partners:

cwlS_3

0.799

CUO07780.1

0.793

CUO08339.1

0.792

traG_2

0.792

traG_3

0.792

CUN67174.1

0.790

CUO79347.1

0.790

CUO05844.1

0.788

CUO98085.1

0.787

CUO08503.1

0.785

Your Current Organism:

Faecalicatena contorta

NCBI taxonomy Id: 39482
Other names: ATCC 25540, CCUG 52236, Catenabacterium contortum, DSM 3982, Eubacterium contortum, F. contorta, JCM 6483

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CUN67174.1	CUO08339.1	ERS852491_00215	ERS852491_01242	Conjugal transfer coupling protein TraG.	Conjugal transfer coupling protein TraG.	0.976
CUN67174.1	CUO08503.1	ERS852491_00215	ERS852491_01247	Conjugal transfer coupling protein TraG.	Uncharacterised protein.	0.774
CUN67174.1	CUO79347.1	ERS852491_00215	ERS852491_03319	Conjugal transfer coupling protein TraG.	Conjugal transfer coupling protein TraG.	0.976
CUN67174.1	CUO98085.1	ERS852491_00215	ERS852491_03913	Conjugal transfer coupling protein TraG.	Uncharacterised protein.	0.756
CUN67174.1	CUP41553.1	ERS852491_00215	ERS852491_05098	Conjugal transfer coupling protein TraG.	Type IV secretory pathway%2C VirB4 components.	0.790
CUO05844.1	CUO08503.1	ERS852491_01163	ERS852491_01247	Conjugal transfer coupling protein TraG.	Uncharacterised protein.	0.757
CUO05844.1	CUO98085.1	ERS852491_01163	ERS852491_03913	Conjugal transfer coupling protein TraG.	Uncharacterised protein.	0.729
CUO05844.1	CUP41553.1	ERS852491_01163	ERS852491_05098	Conjugal transfer coupling protein TraG.	Type IV secretory pathway%2C VirB4 components.	0.788
CUO07780.1	CUO08339.1	ERS852491_01226	ERS852491_01242	Type IV secretion system protein VirD4.	Conjugal transfer coupling protein TraG.	0.976
CUO07780.1	CUO08503.1	ERS852491_01226	ERS852491_01247	Type IV secretion system protein VirD4.	Uncharacterised protein.	0.773
CUO07780.1	CUO79347.1	ERS852491_01226	ERS852491_03319	Type IV secretion system protein VirD4.	Conjugal transfer coupling protein TraG.	0.976
CUO07780.1	CUO98085.1	ERS852491_01226	ERS852491_03913	Type IV secretion system protein VirD4.	Uncharacterised protein.	0.772
CUO07780.1	CUP41553.1	ERS852491_01226	ERS852491_05098	Type IV secretion system protein VirD4.	Type IV secretory pathway%2C VirB4 components.	0.793
CUO08339.1	CUN67174.1	ERS852491_01242	ERS852491_00215	Conjugal transfer coupling protein TraG.	Conjugal transfer coupling protein TraG.	0.976
CUO08339.1	CUO07780.1	ERS852491_01242	ERS852491_01226	Conjugal transfer coupling protein TraG.	Type IV secretion system protein VirD4.	0.976
CUO08339.1	CUO08503.1	ERS852491_01242	ERS852491_01247	Conjugal transfer coupling protein TraG.	Uncharacterised protein.	0.809
CUO08339.1	CUO98085.1	ERS852491_01242	ERS852491_03913	Conjugal transfer coupling protein TraG.	Uncharacterised protein.	0.759
CUO08339.1	CUP41553.1	ERS852491_01242	ERS852491_05098	Conjugal transfer coupling protein TraG.	Type IV secretory pathway%2C VirB4 components.	0.792
CUO08503.1	CUN67174.1	ERS852491_01247	ERS852491_00215	Uncharacterised protein.	Conjugal transfer coupling protein TraG.	0.774
CUO08503.1	CUO05844.1	ERS852491_01247	ERS852491_01163	Uncharacterised protein.	Conjugal transfer coupling protein TraG.	0.757

page 1 of 3

Network Stats

number of nodes:

11

number of edges:

31

average node degree:

5.64

avg. local clustering coefficient:

0.676

expected number of edges:

15

PPI enrichment p-value:

0.000305

your network has significantly more interactions
than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0016491

Oxidoreductase activity

7 of 150

1.2

1.28

4.73e-05

GO:0003824

Catalytic activity

11 of 1226

0.49

0.39

0.0020

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:3266

Oxoacid metabolic process, and Carbon metabolism

9 of 188

1.21

1.64

6.81e-08

CL:3268

Oxoacid metabolic process, and Oxidoreductase activity

8 of 172

1.2

1.5

9.42e-07

CL:3270

Carbon metabolism, and Valine, leucine and isoleucine degradation

5 of 90

1.28

1.14

0.00069

CL:3273

Tricarboxylic acid cycle, and acetyl-CoA biosynthetic process

3 of 26

1.6

1.01

0.0072

CL:3577

Glycine catabolic process, and Pyridine nucleotide-disulphide oxidoreductase

2 of 7

1.99

0.88

0.0218

(more ...)

KEGG Pathways

pathway

description

count in network

strength

signal

false discovery rate

map00650

Butanoate metabolism

2 of 12

1.75

0.71

0.0430

map01100

Metabolic pathways

8 of 603

0.66

0.48

0.0060

Protein Domains (Pfam)

domain

description

count in network

strength

signal

false discovery rate

PF13738

Pyridine nucleotide-disulphide oxidoreductase

2 of 3

2.36

0.81

0.0334

Protein Domains and Features (InterPro)

domain

description

count in network

strength

signal

false discovery rate

IPR036188

FAD/NAD(P)-binding domain superfamily

4 of 16

1.93

1.76

0.00026

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