STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
xptXanthine phosphoribosyltransferase; Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis. (207 aa)    
Predicted Functional Partners:
guaA_2
GMP synthase [glutamine-hydrolyzing]; Catalyzes the synthesis of GMP from XMP.
  
 
 0.932
xanP
Xanthine permease XanP.
  
 0.867
xanQ
Xanthine permease XanQ.
  
 0.862
CUO74535.1
Molybdopterin-guanine dinucleotide biosynthesis protein MobA.
       0.795
purL
Phosphoribosylformylglycinamidine synthase.
  
  
 0.784
hcrA
4-hydroxybenzoyl-CoA reductase subunit alpha.
       0.780
CUO74446.1
Putative oxidoreductase.
       0.774
hcrC
4-hydroxybenzoyl-CoA reductase subunit gamma.
       0.774
purA
Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family.
   
 
 0.685
guaB
Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
  
  
 0.683
Your Current Organism:
Anaerobutyricum hallii
NCBI taxonomy Id: 39488
Other names: A. hallii, ATCC 27751, DSM 3353, Eubacterium hallii, VPI B4-27
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