CUO99013.1 protein (Anaerobutyricum hallii) - STRING interaction network

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second shell of interactors

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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protein homology

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Score

CUO99013.1

Nitrogenase molybdenum-iron protein%2C alpha and beta chains. (457 aa)

Predicted Functional Partners:

CUO98984.1

0.945

nifH1_1

0.932

nifH1_2

0.900

CUO99280.1

0.890

CUO99078.1

0.776

hypC

0.691

nifD

0.678

hypE_2

0.615

xylB

0.571

hypF

0.556

Your Current Organism:

Anaerobutyricum hallii

NCBI taxonomy Id: 39488
Other names: A. hallii, ATCC 27751, DSM 3353, Eubacterium hallii, VPI B4-27

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CUO98984.1	CUO99013.1	ERS852450_02821	ERS852450_02822	Nitrogenase molybdenum-cofactor biosynthesis protein NifE.	Nitrogenase molybdenum-iron protein%2C alpha and beta chains.	0.945
CUO98984.1	CUO99078.1	ERS852450_02821	ERS852450_02824	Nitrogenase molybdenum-cofactor biosynthesis protein NifE.	Putative iron-only hydrogenase system regulator.	0.735
CUO98984.1	CUO99280.1	ERS852450_02821	ERS852450_02829	Nitrogenase molybdenum-cofactor biosynthesis protein NifE.	Nitrogenase molybdenum-cofactor biosynthesis protein NifE.	0.555
CUO98984.1	hypC	ERS852450_02821	ERS852450_02827	Nitrogenase molybdenum-cofactor biosynthesis protein NifE.	Hydrogenase isoenzymes formation protein hypC.	0.583
CUO98984.1	hypE_2	ERS852450_02821	ERS852450_02825	Nitrogenase molybdenum-cofactor biosynthesis protein NifE.	Hydrogenase isoenzymes formation protein hypE.	0.577
CUO98984.1	hypF	ERS852450_02821	ERS852450_02828	Nitrogenase molybdenum-cofactor biosynthesis protein NifE.	Carbamoyltransferase hypF; Belongs to the carbamoyltransferase HypF family.	0.477
CUO98984.1	nifD	ERS852450_02821	ERS852450_02830	Nitrogenase molybdenum-cofactor biosynthesis protein NifE.	Nitrogenase molybdenum-iron protein alpha chain.	0.894
CUO98984.1	nifH1_1	ERS852450_02821	ERS852450_02823	Nitrogenase molybdenum-cofactor biosynthesis protein NifE.	Nitrogenase iron protein 1; Belongs to the NifH/BchL/ChlL family.	0.950
CUO98984.1	nifH1_2	ERS852450_02821	ERS852450_02831	Nitrogenase molybdenum-cofactor biosynthesis protein NifE.	Nitrogenase iron protein 1; Belongs to the NifH/BchL/ChlL family.	0.926
CUO98984.1	xylB	ERS852450_02821	ERS852450_00753	Nitrogenase molybdenum-cofactor biosynthesis protein NifE.	Xylulose kinase.	0.494
CUO99013.1	CUO98984.1	ERS852450_02822	ERS852450_02821	Nitrogenase molybdenum-iron protein%2C alpha and beta chains.	Nitrogenase molybdenum-cofactor biosynthesis protein NifE.	0.945
CUO99013.1	CUO99078.1	ERS852450_02822	ERS852450_02824	Nitrogenase molybdenum-iron protein%2C alpha and beta chains.	Putative iron-only hydrogenase system regulator.	0.776
CUO99013.1	CUO99280.1	ERS852450_02822	ERS852450_02829	Nitrogenase molybdenum-iron protein%2C alpha and beta chains.	Nitrogenase molybdenum-cofactor biosynthesis protein NifE.	0.890
CUO99013.1	hypC	ERS852450_02822	ERS852450_02827	Nitrogenase molybdenum-iron protein%2C alpha and beta chains.	Hydrogenase isoenzymes formation protein hypC.	0.691
CUO99013.1	hypE_2	ERS852450_02822	ERS852450_02825	Nitrogenase molybdenum-iron protein%2C alpha and beta chains.	Hydrogenase isoenzymes formation protein hypE.	0.615
CUO99013.1	hypF	ERS852450_02822	ERS852450_02828	Nitrogenase molybdenum-iron protein%2C alpha and beta chains.	Carbamoyltransferase hypF; Belongs to the carbamoyltransferase HypF family.	0.556
CUO99013.1	nifD	ERS852450_02822	ERS852450_02830	Nitrogenase molybdenum-iron protein%2C alpha and beta chains.	Nitrogenase molybdenum-iron protein alpha chain.	0.678
CUO99013.1	nifH1_1	ERS852450_02822	ERS852450_02823	Nitrogenase molybdenum-iron protein%2C alpha and beta chains.	Nitrogenase iron protein 1; Belongs to the NifH/BchL/ChlL family.	0.932
CUO99013.1	nifH1_2	ERS852450_02822	ERS852450_02831	Nitrogenase molybdenum-iron protein%2C alpha and beta chains.	Nitrogenase iron protein 1; Belongs to the NifH/BchL/ChlL family.	0.900
CUO99013.1	xylB	ERS852450_02822	ERS852450_00753	Nitrogenase molybdenum-iron protein%2C alpha and beta chains.	Xylulose kinase.	0.571

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Network Stats

number of nodes:

8

number of edges:

9

average node degree:

2.25

avg. local clustering coefficient:

0.845

expected number of edges:

7

PPI enrichment p-value:

0.272

your network does not have significantly more
interactions than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0042777

Proton motive force-driven plasma membrane ATP synthesis

4 of 5

2.11

2.54

6.86e-06

GO:0015986

Proton motive force-driven ATP synthesis

5 of 12

1.82

2.46

2.30e-06

GO:1901137

Carbohydrate derivative biosynthetic process

6 of 91

1.02

0.94

0.00030

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0015078

Proton transmembrane transporter activity

9 of 17

1.93

4.75

1.85e-13

GO:0046961

Proton-transporting ATPase activity, rotational mechanism

7 of 9

2.09

4.5

5.80e-11

GO:0046933

Proton-transporting ATP synthase activity, rotational mechanism

6 of 13

1.87

3.27

1.19e-08

Cellular Component (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0016469

Proton-transporting two-sector ATPase complex

9 of 16

1.95

5.08

2.24e-14

GO:0033176

Proton-transporting V-type ATPase complex

4 of 4

2.2

2.93

1.28e-06

GO:0033177

Proton-transporting two-sector ATPase complex, proton-transporting domain

4 of 6

2.03

2.63

3.05e-06

GO:0045259

Proton-transporting ATP synthase complex

4 of 11

1.76

2.1

1.63e-05

GO:0033179

Proton-transporting V-type ATPase, V0 domain

2 of 2

2.2

1.39

0.0024

(more ...)

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:711

ATPase-coupled ion transmembrane transporter activity, and Cation transporter/ATPase, N-terminus

9 of 13

2.04

5.41

2.40e-14

CL:715

Proton motive force-driven plasma membrane ATP synthesis, and Proton-transporting V-type ATPase complex

6 of 6

2.2

4.19

1.34e-09

KEGG Pathways

pathway

description

count in network

strength

signal

false discovery rate

map00190

Oxidative phosphorylation

10 of 27

1.77

4.45

4.90e-15

map01100

Metabolic pathways

10 of 619

0.41

0.31

0.0120

Reactome Pathways

pathway

description

count in network

strength

signal

false discovery rate

MAP-168249

Innate Immune System

7 of 18

1.79

3.61

1.47e-10

MAP-168256

Immune System

7 of 19

1.77

3.54

1.47e-10

Subcellular Localization (COMPARTMENTS)

compartment

description

count in network

strength

signal

false discovery rate

GOCC:0016469

Proton-transporting two-sector ATPase complex

8 of 18

1.85

3.99

2.07e-11

GOCC:0033176

Proton-transporting V-type ATPase complex

5 of 7

2.06

3.17

1.59e-07

GOCC:0033177

Proton-transporting two-sector ATPase complex, proton-transporting domain

3 of 8

1.78

1.42

0.0011

GOCC:0033179

Proton-transporting V-type ATPase, V0 domain

2 of 4

1.9

0.96

0.0141

GOCC:0005773

Vacuole

2 of 5

1.8

0.9

0.0172

(more ...)

Annotated Keywords (UniProt)

keyword

description

count in network

strength

signal

false discovery rate

KW-0406

Ion transport

6 of 15

1.8

2.88

9.41e-08

KW-0375

Hydrogen ion transport

4 of 10

1.8

1.92

6.42e-05

KW-0066

ATP synthesis

4 of 10

1.8

1.92

6.42e-05

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