node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
CUP13821.1 | CUP13866.1 | ERS852450_03138 | ERS852450_03139 | Bifunctional chorismate mutase/prephenate dehydratase. | Uncharacterised protein. | 0.773 |
CUP13821.1 | aroA1 | ERS852450_03138 | ERS852450_03231 | Bifunctional chorismate mutase/prephenate dehydratase. | 3-phosphoshikimate 1-carboxyvinyltransferase 1; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. | 0.875 |
CUP13821.1 | aroC | ERS852450_03138 | ERS852450_00368 | Bifunctional chorismate mutase/prephenate dehydratase. | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. | 0.756 |
CUP13821.1 | aroG | ERS852450_03138 | ERS852450_03065 | Bifunctional chorismate mutase/prephenate dehydratase. | Phospho-2-dehydro-3-deoxyheptonate aldolase%2C Phe-sensitive; Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino- heptulosonate-7-phosphate (DAHP). | 0.688 |
CUP13821.1 | aroK | ERS852450_03138 | ERS852450_02090 | Bifunctional chorismate mutase/prephenate dehydratase. | Shikimate kinase; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family. | 0.794 |
CUP13821.1 | guaB | ERS852450_03138 | ERS852450_00247 | Bifunctional chorismate mutase/prephenate dehydratase. | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.672 |
CUP13821.1 | nadE | ERS852450_03138 | ERS852450_00479 | Bifunctional chorismate mutase/prephenate dehydratase. | Glutamine-dependent NAD(+) synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source. | 0.731 |
CUP13821.1 | rpmC | ERS852450_03138 | ERS852450_00563 | Bifunctional chorismate mutase/prephenate dehydratase. | RRP-L29; Belongs to the universal ribosomal protein uL29 family. | 0.717 |
CUP13821.1 | serC | ERS852450_03138 | ERS852450_01241 | Bifunctional chorismate mutase/prephenate dehydratase. | Phosphoserine aminotransferase; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine. | 0.881 |
CUP13821.1 | tyrC | ERS852450_03138 | ERS852450_00001 | Bifunctional chorismate mutase/prephenate dehydratase. | Arogenate dehydrogenase. | 0.699 |
CUP13866.1 | CUP13821.1 | ERS852450_03139 | ERS852450_03138 | Uncharacterised protein. | Bifunctional chorismate mutase/prephenate dehydratase. | 0.773 |
aroA1 | CUP13821.1 | ERS852450_03231 | ERS852450_03138 | 3-phosphoshikimate 1-carboxyvinyltransferase 1; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. | Bifunctional chorismate mutase/prephenate dehydratase. | 0.875 |
aroA1 | aroC | ERS852450_03231 | ERS852450_00368 | 3-phosphoshikimate 1-carboxyvinyltransferase 1; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. | 0.982 |
aroA1 | aroK | ERS852450_03231 | ERS852450_02090 | 3-phosphoshikimate 1-carboxyvinyltransferase 1; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. | Shikimate kinase; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family. | 0.997 |
aroA1 | serC | ERS852450_03231 | ERS852450_01241 | 3-phosphoshikimate 1-carboxyvinyltransferase 1; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. | Phosphoserine aminotransferase; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine. | 0.631 |
aroA1 | tyrC | ERS852450_03231 | ERS852450_00001 | 3-phosphoshikimate 1-carboxyvinyltransferase 1; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. | Arogenate dehydrogenase. | 0.990 |
aroC | CUP13821.1 | ERS852450_00368 | ERS852450_03138 | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. | Bifunctional chorismate mutase/prephenate dehydratase. | 0.756 |
aroC | aroA1 | ERS852450_00368 | ERS852450_03231 | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. | 3-phosphoshikimate 1-carboxyvinyltransferase 1; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. | 0.982 |
aroC | aroK | ERS852450_00368 | ERS852450_02090 | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. | Shikimate kinase; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family. | 0.942 |
aroC | guaB | ERS852450_00368 | ERS852450_00247 | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.556 |