node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
CUM97886.1 | aroE | ERS852448_01329 | ERS852448_00118 | Putative nicotinate-nucleotide adenylyltransferase. | Shikimate dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). | 0.566 |
CUM97886.1 | mrnC | ERS852448_01329 | ERS852448_00836 | Putative nicotinate-nucleotide adenylyltransferase. | Mini-ribonuclease 3; Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc); Rnc processes 30S rRNA into smaller rRNA precursors; Belongs to the MrnC RNase family. | 0.579 |
CUM97886.1 | nadD | ERS852448_01329 | ERS852448_01328 | Putative nicotinate-nucleotide adenylyltransferase. | Nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). | 0.997 |
CUM97886.1 | nadE | ERS852448_01329 | ERS852448_02874 | Putative nicotinate-nucleotide adenylyltransferase. | Glutamine-dependent NAD(+) synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source. | 0.870 |
CUM97886.1 | obg | ERS852448_01329 | ERS852448_01326 | Putative nicotinate-nucleotide adenylyltransferase. | Spo0B-associated GTP-binding protein; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. | 0.594 |
CUM97886.1 | pncB | ERS852448_01329 | ERS852448_00721 | Putative nicotinate-nucleotide adenylyltransferase. | Nicotinate phosphoribosyltransferase; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family. | 0.807 |
CUM97886.1 | polC_1 | ERS852448_01329 | ERS852448_02169 | Putative nicotinate-nucleotide adenylyltransferase. | DNA polymerase III polC-type; Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity. | 0.586 |
CUM97886.1 | ppnK | ERS852448_01329 | ERS852448_00099 | Putative nicotinate-nucleotide adenylyltransferase. | Probable inorganic polyphosphate/ATP-NAD kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. | 0.767 |
CUM97886.1 | ybeB | ERS852448_01329 | ERS852448_01330 | Putative nicotinate-nucleotide adenylyltransferase. | Ribosome-associated protein; Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation. | 0.945 |
CUM97886.1 | yhbY | ERS852448_01329 | ERS852448_01327 | Putative nicotinate-nucleotide adenylyltransferase. | RNA-binding protein YhbY. | 0.858 |
aroE | CUM97886.1 | ERS852448_00118 | ERS852448_01329 | Shikimate dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). | Putative nicotinate-nucleotide adenylyltransferase. | 0.566 |
aroE | nadD | ERS852448_00118 | ERS852448_01328 | Shikimate dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). | Nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). | 0.731 |
aroE | ybeB | ERS852448_00118 | ERS852448_01330 | Shikimate dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). | Ribosome-associated protein; Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation. | 0.424 |
aroE | yhbY | ERS852448_00118 | ERS852448_01327 | Shikimate dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). | RNA-binding protein YhbY. | 0.523 |
mrnC | CUM97886.1 | ERS852448_00836 | ERS852448_01329 | Mini-ribonuclease 3; Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc); Rnc processes 30S rRNA into smaller rRNA precursors; Belongs to the MrnC RNase family. | Putative nicotinate-nucleotide adenylyltransferase. | 0.579 |
mrnC | polC_1 | ERS852448_00836 | ERS852448_02169 | Mini-ribonuclease 3; Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc); Rnc processes 30S rRNA into smaller rRNA precursors; Belongs to the MrnC RNase family. | DNA polymerase III polC-type; Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity. | 0.531 |
nadD | CUM97886.1 | ERS852448_01328 | ERS852448_01329 | Nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). | Putative nicotinate-nucleotide adenylyltransferase. | 0.997 |
nadD | aroE | ERS852448_01328 | ERS852448_00118 | Nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). | Shikimate dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). | 0.731 |
nadD | nadE | ERS852448_01328 | ERS852448_02874 | Nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). | Glutamine-dependent NAD(+) synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source. | 0.968 |
nadD | obg | ERS852448_01328 | ERS852448_01326 | Nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). | Spo0B-associated GTP-binding protein; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. | 0.699 |