STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
mprFUncharacterised protein family (UPF0104); Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms. (329 aa)    
Predicted Functional Partners:
pat
Phosphinothricin N-acetyltransferase.
   
    0.513
dagK
Diacylglycerol kinase.
  
 
  0.445
CUN20054.1
Putative 2-hydroxyacid dehydrogenase HI_1556; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
  
    0.437
kfoC
Chondroitin polymerase.
  
 
 0.400
yfdH
Bactoprenol glucosyl transferase homolog from prophage CPS-53.
  
 
 0.400
Your Current Organism:
Eubacterium ramulus
NCBI taxonomy Id: 39490
Other names: ATCC 29099, DSM 3995, E. ramulus
Server load: low (22%) [HD]