STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
prfCUnannotated protein; Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily. (536 aa)    
Predicted Functional Partners:
rpmA
Unannotated protein; Belongs to the bacterial ribosomal protein bL27 family.
   
 
 0.944
rplL
Unannotated protein; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation; Belongs to the bacterial ribosomal protein bL12 family.
   
 
 0.905
rplT
Unannotated protein; Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.
  
 
 0.894
rplS
Unannotated protein; This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.
  
   0.894
rplK
Unannotated protein; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
  
 
  0.890
rpmG
Unannotated protein; Belongs to the bacterial ribosomal protein bL33 family.
   
   0.870
rplC
Unannotated protein; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
    
 0.869
rplI
Unannotated protein; Binds to the 23S rRNA.
   
   0.861
rplQ
Unannotated protein.
  
   0.851
rplU
Unannotated protein; This protein binds to 23S rRNA in the presence of protein L20; Belongs to the bacterial ribosomal protein bL21 family.
   
   0.850
Your Current Organism:
Chromobacterium haemolyticum
NCBI taxonomy Id: 394935
Other names: C. haemolyticum, CCUG 53230, Chromobacterium haemolyticum Han et al. 2008, DSM 19808, JCM 14163, strain MDA0585
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