node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
kdsA | kdsB | BMULJ_02092 | BMULJ_02511 | 2-dehydro-3-deoxyphosphooctonate aldolase; COG2877: 3-deoxy-D-manno-octulosonic acid (KDO) 8-phosphate synthase, Ralstonia solanacearum; KEGG, K01627; Belongs to the KdsA family. | 3-deoxy-manno-octulosonate cytidylyltransferase; Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria. | 0.935 |
kdsA | kdsC | BMULJ_02092 | BMULJ_02731 | 2-dehydro-3-deoxyphosphooctonate aldolase; COG2877: 3-deoxy-D-manno-octulosonic acid (KDO) 8-phosphate synthase, Ralstonia solanacearum; KEGG, K01627; Belongs to the KdsA family. | 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase; COG1778: Low specificity phosphatase (HAD superfamily), Ralstonia solanacearum; KEGG, K03270. | 0.998 |
kdsA | kdsD | BMULJ_02092 | BMULJ_02730 | 2-dehydro-3-deoxyphosphooctonate aldolase; COG2877: 3-deoxy-D-manno-octulosonic acid (KDO) 8-phosphate synthase, Ralstonia solanacearum; KEGG, K01627; Belongs to the KdsA family. | COG0794: Predicted sugar phosphate isomerase involved in capsule formation, Ralstonia solanacearum; KEGG, K06041; Belongs to the SIS family. GutQ/KpsF subfamily. | 0.995 |
kdsA | kdtA | BMULJ_02092 | BMULJ_00742 | 2-dehydro-3-deoxyphosphooctonate aldolase; COG2877: 3-deoxy-D-manno-octulosonic acid (KDO) 8-phosphate synthase, Ralstonia solanacearum; KEGG, K01627; Belongs to the KdsA family. | 3-deoxy-D-manno-octulosonic-acid transferase; Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP- Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A; Belongs to the glycosyltransferase group 1 family. | 0.869 |
kdsA | lpxA | BMULJ_02092 | BMULJ_01978 | 2-dehydro-3-deoxyphosphooctonate aldolase; COG2877: 3-deoxy-D-manno-octulosonic acid (KDO) 8-phosphate synthase, Ralstonia solanacearum; KEGG, K01627; Belongs to the KdsA family. | UDP-N-acetylglucosamine acyltransferase; Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. | 0.863 |
kdsA | lpxB | BMULJ_02092 | BMULJ_01977 | 2-dehydro-3-deoxyphosphooctonate aldolase; COG2877: 3-deoxy-D-manno-octulosonic acid (KDO) 8-phosphate synthase, Ralstonia solanacearum; KEGG, K01627; Belongs to the KdsA family. | lipid-A-disaccharide synthase; Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. | 0.864 |
kdsA | lpxC | BMULJ_02092 | BMULJ_00409 | 2-dehydro-3-deoxyphosphooctonate aldolase; COG2877: 3-deoxy-D-manno-octulosonic acid (KDO) 8-phosphate synthase, Ralstonia solanacearum; KEGG, K01627; Belongs to the KdsA family. | UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase; Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis; Belongs to the LpxC family. | 0.868 |
kdsA | lpxD | BMULJ_02092 | BMULJ_01980 | 2-dehydro-3-deoxyphosphooctonate aldolase; COG2877: 3-deoxy-D-manno-octulosonic acid (KDO) 8-phosphate synthase, Ralstonia solanacearum; KEGG, K01627; Belongs to the KdsA family. | UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase; Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3- hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. Belongs to the transferase hexapeptide repeat family. LpxD subfamily. | 0.861 |
kdsA | lpxK | BMULJ_02092 | BMULJ_02509 | 2-dehydro-3-deoxyphosphooctonate aldolase; COG2877: 3-deoxy-D-manno-octulosonic acid (KDO) 8-phosphate synthase, Ralstonia solanacearum; KEGG, K01627; Belongs to the KdsA family. | Tetraacyldisaccharide 4'-kinase; Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA). | 0.865 |
kdsA | pyrG | BMULJ_02092 | BMULJ_02093 | 2-dehydro-3-deoxyphosphooctonate aldolase; COG2877: 3-deoxy-D-manno-octulosonic acid (KDO) 8-phosphate synthase, Ralstonia solanacearum; KEGG, K01627; Belongs to the KdsA family. | CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates. | 0.835 |
kdsB | kdsA | BMULJ_02511 | BMULJ_02092 | 3-deoxy-manno-octulosonate cytidylyltransferase; Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria. | 2-dehydro-3-deoxyphosphooctonate aldolase; COG2877: 3-deoxy-D-manno-octulosonic acid (KDO) 8-phosphate synthase, Ralstonia solanacearum; KEGG, K01627; Belongs to the KdsA family. | 0.935 |
kdsB | kdsC | BMULJ_02511 | BMULJ_02731 | 3-deoxy-manno-octulosonate cytidylyltransferase; Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria. | 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase; COG1778: Low specificity phosphatase (HAD superfamily), Ralstonia solanacearum; KEGG, K03270. | 0.995 |
kdsB | kdsD | BMULJ_02511 | BMULJ_02730 | 3-deoxy-manno-octulosonate cytidylyltransferase; Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria. | COG0794: Predicted sugar phosphate isomerase involved in capsule formation, Ralstonia solanacearum; KEGG, K06041; Belongs to the SIS family. GutQ/KpsF subfamily. | 0.896 |
kdsB | kdtA | BMULJ_02511 | BMULJ_00742 | 3-deoxy-manno-octulosonate cytidylyltransferase; Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria. | 3-deoxy-D-manno-octulosonic-acid transferase; Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP- Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A; Belongs to the glycosyltransferase group 1 family. | 0.993 |
kdsB | lpxA | BMULJ_02511 | BMULJ_01978 | 3-deoxy-manno-octulosonate cytidylyltransferase; Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria. | UDP-N-acetylglucosamine acyltransferase; Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. | 0.870 |
kdsB | lpxB | BMULJ_02511 | BMULJ_01977 | 3-deoxy-manno-octulosonate cytidylyltransferase; Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria. | lipid-A-disaccharide synthase; Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. | 0.868 |
kdsB | lpxC | BMULJ_02511 | BMULJ_00409 | 3-deoxy-manno-octulosonate cytidylyltransferase; Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria. | UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase; Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis; Belongs to the LpxC family. | 0.868 |
kdsB | lpxD | BMULJ_02511 | BMULJ_01980 | 3-deoxy-manno-octulosonate cytidylyltransferase; Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria. | UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase; Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3- hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. Belongs to the transferase hexapeptide repeat family. LpxD subfamily. | 0.869 |
kdsB | lpxK | BMULJ_02511 | BMULJ_02509 | 3-deoxy-manno-octulosonate cytidylyltransferase; Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria. | Tetraacyldisaccharide 4'-kinase; Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA). | 0.967 |
kdsC | kdsA | BMULJ_02731 | BMULJ_02092 | 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase; COG1778: Low specificity phosphatase (HAD superfamily), Ralstonia solanacearum; KEGG, K03270. | 2-dehydro-3-deoxyphosphooctonate aldolase; COG2877: 3-deoxy-D-manno-octulosonic acid (KDO) 8-phosphate synthase, Ralstonia solanacearum; KEGG, K01627; Belongs to the KdsA family. | 0.998 |