STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
acdS1-aminocyclopropane-1-carboxylate deaminase; Catalyzes a cyclopropane ring-opening reaction, the irreversible conversion of 1-aminocyclopropane-1-carboxylate (ACC) to ammonia and alpha-ketobutyrate. Allows growth on ACC as a nitrogen source; Belongs to the ACC deaminase/D-cysteine desulfhydrase family. (338 aa)    
Predicted Functional Partners:
BAG45179.1
COG1522: Transcriptional regulators, Ralstonia solanacearum.
 
   
 0.624
BAG46033.1
COG0607: Rhodanese-related sulfurtransferase, Pseudomonas aeruginosa.
  
 
  0.592
ybiC-2
COG2055: Malate/L-lactate dehydrogenases, Escherichia coli O157:H7; KEGG, K00025; Belongs to the LDH2/MDH2 oxidoreductase family.
  
  
  0.591
metC
COG0626: Cystathionine beta-lyases/cystathionine gamma-synthases, Ralstonia solanacearum; KEGG, K01760.
     
 0.543
sseA-3
COG2897: Rhodanese-related sulfurtransferase, Ralstonia solanacearum; KEGG, K01010.
    
  0.526
recA
Recombination protein; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family.
      
 0.506
metB
Cystathionine gamma-synthase; Catalyzes the formation of L-homocysteine from O-succinyl-L- homoserine (OSHS) and hydrogen sulfide.
     
 0.483
ybiC
Malate dehydrogenase; Catalyzes the reduction of Delta(1)-pyrroline-2-carboxylate (Pyr2C) to L-proline, using NADPH as the electron donor. May be involved in a degradation pathway that converts trans-3-hydroxy-L- proline (t3LHyp) to L-proline.
  
  
  0.435
rpoB
DNA-directed RNA polymerase, beta subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
      
 0.430
BAG44783.1
COG4231: Indolepyruvate ferredoxin oxidoreductase, alpha and beta subunits, Ralstonia solanacearum; KEGG, K04090.
     
 0.422
Your Current Organism:
Burkholderia multivorans
NCBI taxonomy Id: 395019
Other names: B. multivorans ATCC 17616, Burkholderia multivorans ATCC 17616, Burkholderia multivorans str. ATCC 17616, Burkholderia multivorans strain ATCC 17616
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