STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Galf_0009PFAM: AMP-dependent synthetase and ligase; KEGG: AMP-dependent synthetase and ligase. (543 aa)    
Predicted Functional Partners:
Galf_0094
TIGRFAM: 2-methylcitrate synthase/citrate synthase II; KEGG: slt:Slit_1189 2-methylcitrate synthase/citrate synthase II; PFAM: Citrate synthase; Belongs to the citrate synthase family.
  
 0.958
Galf_1336
TIGRFAM: citrate synthase I; KEGG: slt:Slit_1836 citrate synthase I; PFAM: Citrate synthase; Belongs to the citrate synthase family.
  
 0.958
Galf_0097
PFAM: AMP-dependent synthetase and ligase; KEGG: slt:Slit_1187 AMP-dependent synthetase and ligase.
  
  
 
0.926
ackA
Acetate and butyrate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family.
   
 
 0.924
acsA
acetate/CoA ligase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family.
  
  
 
0.924
Galf_2882
acetyl-CoA carboxylase, biotin carboxylase; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.
 
 0.923
Galf_0349
TIGRFAM: 2-isopropylmalate synthase/homocitrate synthase family protein; KEGG: app:CAP2UW1_1241 2-isopropylmalate synthase/homocitrate synthase family protein; PFAM: pyruvate carboxyltransferase; LeuA allosteric (dimerisation) domain-containing protein; Belongs to the alpha-IPM synthase/homocitrate synthase family.
  
 
 0.917
leuA
2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.
  
 
 0.917
Galf_0061
PFAM: pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; Transketolase domain-containing protein; KEGG: lch:Lcho_2150 pyruvate flavodoxin/ferredoxin oxidoreductase domain-containing protein.
  
 
 0.912
Galf_0062
TIGRFAM: pyruvate/ketoisovalerate oxidoreductase, gamma subunit; KEGG: app:CAP2UW1_2510 pyruvate/ketoisovalerate oxidoreductase, gamma subunit; PFAM: Pyruvate/ketoisovalerate oxidoreductase, catalytic domain.
  
 
 0.911
Your Current Organism:
Gallionella capsiferriformans
NCBI taxonomy Id: 395494
Other names: G. capsiferriformans ES-2, Gallionella capsiferriformans ES-2, Gallionella capsiferriformans str. ES-2, Gallionella capsiferriformans strain ES-2, Gallionella ferruginea ES-2, Gallionella ferruginea subsp. capsiferriformans ES-2
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