node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Galf_0150 | Galf_0151 | Galf_0150 | Galf_0151 | TIGRFAM: lactoylglutathione lyase; KEGG: net:Neut_1541 lactoylglutathione lyase; PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase. | KEGG: slt:Slit_0041 phosphomethylpyrimidine kinase; PFAM: Phosphomethylpyrimidine kinase type-1. | 0.592 |
Galf_0150 | engB | Galf_0150 | Galf_0154 | TIGRFAM: lactoylglutathione lyase; KEGG: net:Neut_1541 lactoylglutathione lyase; PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase. | Ribosome biogenesis GTP-binding protein YsxC; Necessary for normal cell division and for the maintenance of normal septation; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family. | 0.533 |
Galf_0150 | hemL | Galf_0150 | Galf_0153 | TIGRFAM: lactoylglutathione lyase; KEGG: net:Neut_1541 lactoylglutathione lyase; PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase. | KEGG: slt:Slit_0039 glutamate-1-semialdehyde-2,1-aminomutase; TIGRFAM: glutamate-1-semialdehyde-2,1-aminomutase; PFAM: aminotransferase class-III. | 0.572 |
Galf_0150 | thiE | Galf_0150 | Galf_0152 | TIGRFAM: lactoylglutathione lyase; KEGG: net:Neut_1541 lactoylglutathione lyase; PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase. | Thiamine-phosphate pyrophosphorylase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family. | 0.588 |
Galf_0151 | Galf_0150 | Galf_0151 | Galf_0150 | KEGG: slt:Slit_0041 phosphomethylpyrimidine kinase; PFAM: Phosphomethylpyrimidine kinase type-1. | TIGRFAM: lactoylglutathione lyase; KEGG: net:Neut_1541 lactoylglutathione lyase; PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase. | 0.592 |
Galf_0151 | Galf_0155 | Galf_0151 | Galf_0155 | KEGG: slt:Slit_0041 phosphomethylpyrimidine kinase; PFAM: Phosphomethylpyrimidine kinase type-1. | KEGG: slt:Slit_0037 porphobilinogen synthase; PFAM: delta-aminolevulinic acid dehydratase; Belongs to the ALAD family. | 0.544 |
Galf_0151 | cysG | Galf_0151 | Galf_1602 | KEGG: slt:Slit_0041 phosphomethylpyrimidine kinase; PFAM: Phosphomethylpyrimidine kinase type-1. | uroporphyrin-III C-methyltransferase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. Belongs to the precorrin methyltransferase family. In the N-terminal section; belongs to the precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase family. | 0.427 |
Galf_0151 | engB | Galf_0151 | Galf_0154 | KEGG: slt:Slit_0041 phosphomethylpyrimidine kinase; PFAM: Phosphomethylpyrimidine kinase type-1. | Ribosome biogenesis GTP-binding protein YsxC; Necessary for normal cell division and for the maintenance of normal septation; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family. | 0.783 |
Galf_0151 | hemL | Galf_0151 | Galf_0153 | KEGG: slt:Slit_0041 phosphomethylpyrimidine kinase; PFAM: Phosphomethylpyrimidine kinase type-1. | KEGG: slt:Slit_0039 glutamate-1-semialdehyde-2,1-aminomutase; TIGRFAM: glutamate-1-semialdehyde-2,1-aminomutase; PFAM: aminotransferase class-III. | 0.810 |
Galf_0151 | thiE | Galf_0151 | Galf_0152 | KEGG: slt:Slit_0041 phosphomethylpyrimidine kinase; PFAM: Phosphomethylpyrimidine kinase type-1. | Thiamine-phosphate pyrophosphorylase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family. | 0.999 |
Galf_0155 | Galf_0151 | Galf_0155 | Galf_0151 | KEGG: slt:Slit_0037 porphobilinogen synthase; PFAM: delta-aminolevulinic acid dehydratase; Belongs to the ALAD family. | KEGG: slt:Slit_0041 phosphomethylpyrimidine kinase; PFAM: Phosphomethylpyrimidine kinase type-1. | 0.544 |
Galf_0155 | Galf_2510 | Galf_0155 | Galf_2510 | KEGG: slt:Slit_0037 porphobilinogen synthase; PFAM: delta-aminolevulinic acid dehydratase; Belongs to the ALAD family. | Uroporphyrinogen III synthase HEM4; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. | 0.904 |
Galf_0155 | cysG | Galf_0155 | Galf_1602 | KEGG: slt:Slit_0037 porphobilinogen synthase; PFAM: delta-aminolevulinic acid dehydratase; Belongs to the ALAD family. | uroporphyrin-III C-methyltransferase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. Belongs to the precorrin methyltransferase family. In the N-terminal section; belongs to the precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase family. | 0.906 |
Galf_0155 | engB | Galf_0155 | Galf_0154 | KEGG: slt:Slit_0037 porphobilinogen synthase; PFAM: delta-aminolevulinic acid dehydratase; Belongs to the ALAD family. | Ribosome biogenesis GTP-binding protein YsxC; Necessary for normal cell division and for the maintenance of normal septation; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family. | 0.536 |
Galf_0155 | hemA | Galf_0155 | Galf_2540 | KEGG: slt:Slit_0037 porphobilinogen synthase; PFAM: delta-aminolevulinic acid dehydratase; Belongs to the ALAD family. | glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). | 0.884 |
Galf_0155 | hemC | Galf_0155 | Galf_2511 | KEGG: slt:Slit_0037 porphobilinogen synthase; PFAM: delta-aminolevulinic acid dehydratase; Belongs to the ALAD family. | Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family. | 0.996 |
Galf_0155 | hemE | Galf_0155 | Galf_0176 | KEGG: slt:Slit_0037 porphobilinogen synthase; PFAM: delta-aminolevulinic acid dehydratase; Belongs to the ALAD family. | Uroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III. | 0.715 |
Galf_0155 | hemL | Galf_0155 | Galf_0153 | KEGG: slt:Slit_0037 porphobilinogen synthase; PFAM: delta-aminolevulinic acid dehydratase; Belongs to the ALAD family. | KEGG: slt:Slit_0039 glutamate-1-semialdehyde-2,1-aminomutase; TIGRFAM: glutamate-1-semialdehyde-2,1-aminomutase; PFAM: aminotransferase class-III. | 0.996 |
Galf_0155 | thiE | Galf_0155 | Galf_0152 | KEGG: slt:Slit_0037 porphobilinogen synthase; PFAM: delta-aminolevulinic acid dehydratase; Belongs to the ALAD family. | Thiamine-phosphate pyrophosphorylase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family. | 0.511 |
Galf_2510 | Galf_0155 | Galf_2510 | Galf_0155 | Uroporphyrinogen III synthase HEM4; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. | KEGG: slt:Slit_0037 porphobilinogen synthase; PFAM: delta-aminolevulinic acid dehydratase; Belongs to the ALAD family. | 0.904 |