node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Galf_0440 | Galf_0444 | Galf_0440 | Galf_0444 | PFAM: histidine triad (HIT) protein; KEGG: slt:Slit_0631 histidine triad (HIT) protein. | PFAM: MscS Mechanosensitive ion channel; KEGG: mei:Msip34_0332 MscS mechanosensitive ion channel. | 0.726 |
Galf_0440 | hisA | Galf_0440 | Galf_0436 | PFAM: histidine triad (HIT) protein; KEGG: slt:Slit_0631 histidine triad (HIT) protein. | TIGRFAM: phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase; KEGG: slt:Slit_0627 phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase; PFAM: histidine biosynthesis protein. | 0.800 |
Galf_0440 | hisB | Galf_0440 | Galf_0434 | PFAM: histidine triad (HIT) protein; KEGG: slt:Slit_0631 histidine triad (HIT) protein. | KEGG: slt:Slit_0625 imidazoleglycerol-phosphate dehydratase; PFAM: imidazoleglycerol-phosphate dehydratase. | 0.756 |
Galf_0440 | hisE | Galf_0440 | Galf_0439 | PFAM: histidine triad (HIT) protein; KEGG: slt:Slit_0631 histidine triad (HIT) protein. | KEGG: slt:Slit_0630 phosphoribosyl-ATP diphosphatase; TIGRFAM: phosphoribosyl-ATP diphosphatase; PFAM: Phosphoribosyl-ATP pyrophosphohydrolase-like. | 0.800 |
Galf_0440 | hisF | Galf_0440 | Galf_0437 | PFAM: histidine triad (HIT) protein; KEGG: slt:Slit_0631 histidine triad (HIT) protein. | Imidazoleglycerol phosphate synthase, cyclase subunit; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit. | 0.800 |
Galf_0440 | hisH | Galf_0440 | Galf_0435 | PFAM: histidine triad (HIT) protein; KEGG: slt:Slit_0631 histidine triad (HIT) protein. | Imidazole glycerol phosphate synthase, glutamine amidotransferase subunit; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF. | 0.784 |
Galf_0440 | hisI | Galf_0440 | Galf_0438 | PFAM: histidine triad (HIT) protein; KEGG: slt:Slit_0631 histidine triad (HIT) protein. | Phosphoribosyl-AMP cyclohydrolase; Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP. | 0.801 |
Galf_0440 | tatA | Galf_0440 | Galf_0441 | PFAM: histidine triad (HIT) protein; KEGG: slt:Slit_0631 histidine triad (HIT) protein. | Twin-arginine translocation protein, TatA/E family subunit; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system. | 0.798 |
Galf_0440 | tatB | Galf_0440 | Galf_0442 | PFAM: histidine triad (HIT) protein; KEGG: slt:Slit_0631 histidine triad (HIT) protein. | Twin-arginine translocation protein, TatB subunit; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation. | 0.797 |
Galf_0440 | tatC | Galf_0440 | Galf_0443 | PFAM: histidine triad (HIT) protein; KEGG: slt:Slit_0631 histidine triad (HIT) protein. | Sec-independent protein translocase, TatC subunit; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides. | 0.753 |
Galf_0444 | Galf_0440 | Galf_0444 | Galf_0440 | PFAM: MscS Mechanosensitive ion channel; KEGG: mei:Msip34_0332 MscS mechanosensitive ion channel. | PFAM: histidine triad (HIT) protein; KEGG: slt:Slit_0631 histidine triad (HIT) protein. | 0.726 |
Galf_0444 | hisA | Galf_0444 | Galf_0436 | PFAM: MscS Mechanosensitive ion channel; KEGG: mei:Msip34_0332 MscS mechanosensitive ion channel. | TIGRFAM: phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase; KEGG: slt:Slit_0627 phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase; PFAM: histidine biosynthesis protein. | 0.727 |
Galf_0444 | hisB | Galf_0444 | Galf_0434 | PFAM: MscS Mechanosensitive ion channel; KEGG: mei:Msip34_0332 MscS mechanosensitive ion channel. | KEGG: slt:Slit_0625 imidazoleglycerol-phosphate dehydratase; PFAM: imidazoleglycerol-phosphate dehydratase. | 0.683 |
Galf_0444 | hisE | Galf_0444 | Galf_0439 | PFAM: MscS Mechanosensitive ion channel; KEGG: mei:Msip34_0332 MscS mechanosensitive ion channel. | KEGG: slt:Slit_0630 phosphoribosyl-ATP diphosphatase; TIGRFAM: phosphoribosyl-ATP diphosphatase; PFAM: Phosphoribosyl-ATP pyrophosphohydrolase-like. | 0.718 |
Galf_0444 | hisF | Galf_0444 | Galf_0437 | PFAM: MscS Mechanosensitive ion channel; KEGG: mei:Msip34_0332 MscS mechanosensitive ion channel. | Imidazoleglycerol phosphate synthase, cyclase subunit; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit. | 0.718 |
Galf_0444 | hisH | Galf_0444 | Galf_0435 | PFAM: MscS Mechanosensitive ion channel; KEGG: mei:Msip34_0332 MscS mechanosensitive ion channel. | Imidazole glycerol phosphate synthase, glutamine amidotransferase subunit; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF. | 0.681 |
Galf_0444 | hisI | Galf_0444 | Galf_0438 | PFAM: MscS Mechanosensitive ion channel; KEGG: mei:Msip34_0332 MscS mechanosensitive ion channel. | Phosphoribosyl-AMP cyclohydrolase; Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP. | 0.718 |
Galf_0444 | tatA | Galf_0444 | Galf_0441 | PFAM: MscS Mechanosensitive ion channel; KEGG: mei:Msip34_0332 MscS mechanosensitive ion channel. | Twin-arginine translocation protein, TatA/E family subunit; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system. | 0.773 |
Galf_0444 | tatB | Galf_0444 | Galf_0442 | PFAM: MscS Mechanosensitive ion channel; KEGG: mei:Msip34_0332 MscS mechanosensitive ion channel. | Twin-arginine translocation protein, TatB subunit; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation. | 0.773 |
Galf_0444 | tatC | Galf_0444 | Galf_0443 | PFAM: MscS Mechanosensitive ion channel; KEGG: mei:Msip34_0332 MscS mechanosensitive ion channel. | Sec-independent protein translocase, TatC subunit; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides. | 0.775 |