STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
Galf_1573(NiFe) hydrogenase maturation protein HypF; Involved in the maturation of [NiFe] hydrogenases. Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of [NiFe]-hydrogenases. HypF functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide. (772 aa)    
Predicted Functional Partners:
Galf_1568
KEGG: slt:Slit_2419 hydrogenase expression/formation protein HypE; TIGRFAM: hydrogenase expression/formation protein HypE; PFAM: AIR synthase related protein domain protein; AIR synthase related protein.
 
 
 0.994
Galf_1574
KEGG: slt:Slit_2424 hydrogenase accessory protein HypB; TIGRFAM: hydrogenase accessory protein HypB; PFAM: cobalamin synthesis protein P47K.
 
   
 0.969
Galf_1570
KEGG: slt:Slit_2422 hydrogenase assembly chaperone HypC/HupF; TIGRFAM: hydrogenase assembly chaperone hypC/hupF; PFAM: hydrogenase expression/formation protein (HUPF/HYPC).
 
 
 0.944
Galf_1569
KEGG: slt:Slit_2421 hydrogenase expression/formation protein HypD; TIGRFAM: hydrogenase expression/formation protein HypD; PFAM: hydrogenase formation HypD protein; Belongs to the HypD family.
 
  
 0.943
hypA
Hydrogenase nickel insertion protein HypA; Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.
 
   
 0.894
Galf_1584
PFAM: nickel-dependent hydrogenase large subunit; KEGG: dar:Daro_0982 nickel-dependent hydrogenase, large subunit; Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family.
 
   
 0.648
Galf_1581
PFAM: Respiratory-chain NADH dehydrogenase domain 51 kDa subunit; NADH ubiquinone oxidoreductase, F subunit, iron sulphur binding; NADH dehydrogenase (ubiquinone) 24 kDa subunit; KEGG: slt:Slit_1608 respiratory-chain NADH dehydrogenase domain 51 kDa subunit.
  
  
 0.616
Galf_1585
KEGG: dar:Daro_0983 HoxW protein.
     
 0.564
pfkA
Phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. Mixed-substrate PFK group III subfamily.
     
 0.547
Galf_2380
PFAM: NADH dehydrogenase (ubiquinone) 30 kDa subunit; NADH-ubiquinone oxidoreductase chain 49kDa; KEGG: slt:Slit_2560 NADH dehydrogenase (ubiquinone) 30 kDa subunit.
     
 0.530
Your Current Organism:
Gallionella capsiferriformans
NCBI taxonomy Id: 395494
Other names: G. capsiferriformans ES-2, Gallionella capsiferriformans ES-2, Gallionella capsiferriformans str. ES-2, Gallionella capsiferriformans strain ES-2, Gallionella ferruginea ES-2, Gallionella ferruginea subsp. capsiferriformans ES-2
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