STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
cyaYIron donor protein CyaY; Involved in iron-sulfur (Fe-S) cluster assembly. May act as a regulator of Fe-S biogenesis. (101 aa)    
Predicted Functional Partners:
Galf_0645
FeS cluster assembly scaffold IscU; A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters.
  
 
 0.995
iscS
Cysteine desulfurase IscS; Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins.
  
 0.993
Galf_0649
Ferredoxin, 2Fe-2S type, ISC system; KEGG: rme:Rmet_1030 ferredoxin, 2Fe-2S type; TIGRFAM: ferredoxin, 2Fe-2S type, ISC system; PFAM: ferredoxin.
  
 
 0.870
hscB
Co-chaperone Hsc20; Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA; Belongs to the HscB family.
  
 
 0.801
hemH
Ferrochelatase; Catalyzes the ferrous insertion into protoporphyrin IX. Belongs to the ferrochelatase family.
    
 
 0.751
Galf_0650
KEGG: slt:Slit_2249 FeS assembly protein IscX; TIGRFAM: FeS assembly protein IscX; PFAM: protein of unknown function DUF528.
  
  
 0.693
hscA
Fe-S protein assembly chaperone HscA; Chaperone involved in the maturation of iron-sulfur cluster- containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB.
  
 
 
 0.673
Galf_1860
PFAM: 3-hydroxyacyl-CoA dehydrogenase NAD-binding; 3-hydroxyacyl-CoA dehydrogenase domain-containing protein; Enoyl-CoA hydratase/isomerase; KEGG: slt:Slit_1856 3-hydroxyacyl-CoA dehydrogenase NAD-binding protein.
    
 
 0.668
msrB
PFAM: Methionine sulfoxide reductase B; manually curated; KEGG: slt:Slit_1996 methionine-R-sulfoxide reductase; TIGRFAM: methionine-R-sulfoxide reductase; Belongs to the MsrB Met sulfoxide reductase family.
    
   0.661
rpsI
PFAM: ribosomal protein S9; KEGG: slt:Slit_2456 ribosomal protein S9; Belongs to the universal ribosomal protein uS9 family.
   
   0.647
Your Current Organism:
Gallionella capsiferriformans
NCBI taxonomy Id: 395494
Other names: G. capsiferriformans ES-2, Gallionella capsiferriformans ES-2, Gallionella capsiferriformans str. ES-2, Gallionella capsiferriformans strain ES-2, Gallionella ferruginea ES-2, Gallionella ferruginea subsp. capsiferriformans ES-2
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