node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Galf_0912 | Galf_1208 | Galf_0912 | Galf_1208 | PFAM: StbA family protein; KEGG: shw:Sputw3181_1079 hypothetical protein. | KEGG: cco:CCC13826_1065 DnaJ domain-containing protein; PFAM: heat shock protein DnaJ domain protein; SMART: heat shock protein DnaJ domain protein. | 0.897 |
Galf_0912 | clpP | Galf_0912 | Galf_1627 | PFAM: StbA family protein; KEGG: shw:Sputw3181_1079 hypothetical protein. | ATP-dependent Clp protease, proteolytic subunit ClpP; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family. | 0.628 |
Galf_0912 | dnaJ | Galf_0912 | Galf_2438 | PFAM: StbA family protein; KEGG: shw:Sputw3181_1079 hypothetical protein. | Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...] | 0.897 |
Galf_0912 | groL | Galf_0912 | Galf_2635 | PFAM: StbA family protein; KEGG: shw:Sputw3181_1079 hypothetical protein. | Chaperonin GroEL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. | 0.879 |
Galf_0912 | groS | Galf_0912 | Galf_2636 | PFAM: StbA family protein; KEGG: shw:Sputw3181_1079 hypothetical protein. | Chaperonin Cpn10; Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter. | 0.835 |
Galf_0912 | grpE | Galf_0912 | Galf_2436 | PFAM: StbA family protein; KEGG: shw:Sputw3181_1079 hypothetical protein. | GrpE protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent i [...] | 0.931 |
Galf_0912 | htpG | Galf_0912 | Galf_2693 | PFAM: StbA family protein; KEGG: shw:Sputw3181_1079 hypothetical protein. | Heat shock protein Hsp90-like; Molecular chaperone. Has ATPase activity. | 0.949 |
Galf_1208 | Galf_0912 | Galf_1208 | Galf_0912 | KEGG: cco:CCC13826_1065 DnaJ domain-containing protein; PFAM: heat shock protein DnaJ domain protein; SMART: heat shock protein DnaJ domain protein. | PFAM: StbA family protein; KEGG: shw:Sputw3181_1079 hypothetical protein. | 0.897 |
Galf_1208 | clpP | Galf_1208 | Galf_1627 | KEGG: cco:CCC13826_1065 DnaJ domain-containing protein; PFAM: heat shock protein DnaJ domain protein; SMART: heat shock protein DnaJ domain protein. | ATP-dependent Clp protease, proteolytic subunit ClpP; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family. | 0.566 |
Galf_1208 | dnaK | Galf_1208 | Galf_2437 | KEGG: cco:CCC13826_1065 DnaJ domain-containing protein; PFAM: heat shock protein DnaJ domain protein; SMART: heat shock protein DnaJ domain protein. | Chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family. | 0.978 |
Galf_1208 | groL | Galf_1208 | Galf_2635 | KEGG: cco:CCC13826_1065 DnaJ domain-containing protein; PFAM: heat shock protein DnaJ domain protein; SMART: heat shock protein DnaJ domain protein. | Chaperonin GroEL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. | 0.826 |
Galf_1208 | groS | Galf_1208 | Galf_2636 | KEGG: cco:CCC13826_1065 DnaJ domain-containing protein; PFAM: heat shock protein DnaJ domain protein; SMART: heat shock protein DnaJ domain protein. | Chaperonin Cpn10; Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter. | 0.705 |
Galf_1208 | grpE | Galf_1208 | Galf_2436 | KEGG: cco:CCC13826_1065 DnaJ domain-containing protein; PFAM: heat shock protein DnaJ domain protein; SMART: heat shock protein DnaJ domain protein. | GrpE protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent i [...] | 0.944 |
Galf_1208 | hscA | Galf_1208 | Galf_0648 | KEGG: cco:CCC13826_1065 DnaJ domain-containing protein; PFAM: heat shock protein DnaJ domain protein; SMART: heat shock protein DnaJ domain protein. | Fe-S protein assembly chaperone HscA; Chaperone involved in the maturation of iron-sulfur cluster- containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB. | 0.976 |
Galf_1208 | htpG | Galf_1208 | Galf_2693 | KEGG: cco:CCC13826_1065 DnaJ domain-containing protein; PFAM: heat shock protein DnaJ domain protein; SMART: heat shock protein DnaJ domain protein. | Heat shock protein Hsp90-like; Molecular chaperone. Has ATPase activity. | 0.949 |
clpP | Galf_0912 | Galf_1627 | Galf_0912 | ATP-dependent Clp protease, proteolytic subunit ClpP; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family. | PFAM: StbA family protein; KEGG: shw:Sputw3181_1079 hypothetical protein. | 0.628 |
clpP | Galf_1208 | Galf_1627 | Galf_1208 | ATP-dependent Clp protease, proteolytic subunit ClpP; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family. | KEGG: cco:CCC13826_1065 DnaJ domain-containing protein; PFAM: heat shock protein DnaJ domain protein; SMART: heat shock protein DnaJ domain protein. | 0.566 |
clpP | dnaJ | Galf_1627 | Galf_2438 | ATP-dependent Clp protease, proteolytic subunit ClpP; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family. | Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...] | 0.566 |
clpP | dnaK | Galf_1627 | Galf_2437 | ATP-dependent Clp protease, proteolytic subunit ClpP; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family. | Chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family. | 0.652 |
clpP | groL | Galf_1627 | Galf_2635 | ATP-dependent Clp protease, proteolytic subunit ClpP; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family. | Chaperonin GroEL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. | 0.820 |