STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Lcho_0004KEGG: pna:Pnap_1125 hypothetical protein. (170 aa)    
Predicted Functional Partners:
Lcho_2465
Phage shock protein A, PspA; PFAM: PspA/IM30 family protein; KEGG: pna:Pnap_3139 phage shock protein A, PspA.
 
  
 0.667
Lcho_0655
KEGG: lma:LmjF35.0290 hypothetical protein, conserved.
  
     0.461
Lcho_3184
PFAM: peptidase C14 caspase catalytic subunit p20; KEGG: mpt:Mpe_A1486 hypothetical protein.
  
   
 0.456
gyrB
DNA gyrase, B subunit; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
       0.445
Lcho_2464
PFAM: AAA ATPase central domain protein; SMART: AAA ATPase; KEGG: pna:Pnap_3140 AAA ATPase, central domain protein.
 
     0.436
Lcho_3720
KEGG: pna:Pnap_3103 hypothetical protein.
  
     0.416
Your Current Organism:
Leptothrix cholodnii
NCBI taxonomy Id: 395495
Other names: L. cholodnii SP-6, Leptothrix cholodnii SP-6, Leptothrix cholodnii str. SP-6, Leptothrix cholodnii strain SP-6
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.