STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Lcho_0054Histidine kinase; PFAM: ATP-binding region ATPase domain protein; KEGG: rru:Rru_A3213 PAS/PAC sensor signal transduction histidine kinase. (215 aa)    
Predicted Functional Partners:
Lcho_0045
PFAM: adenylyl cyclase class-3/4/guanylyl cyclase; response regulator receiver; KEGG: rpb:RPB_0891 adenylate/guanylate cyclase.
 
 0.952
Lcho_0046
PFAM: response regulator receiver; KEGG: xau:Xaut_3859 response regulator receiver protein.
 
 0.940
Lcho_4176
PFAM: response regulator receiver; KEGG: azo:azo1491 probable polar differentiation response regulator.
 
 0.873
Lcho_3544
TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; response regulator receiver; KEGG: ppd:Ppro_1341 response regulator receiver modulated diguanylate cyclase.
 
 
 0.856
Lcho_2296
PFAM: response regulator receiver; ATP-binding region ATPase domain protein; histidine kinase A domain protein; KEGG: syn:sll1555 two-component hybrid histidine kinase.
 
 
 0.835
Lcho_0237
PFAM: response regulator receiver; KEGG: rfr:Rfer_3778 response regulator receiver domain protein.
 
 0.834
Lcho_3970
PFAM: response regulator receiver; KEGG: mpt:Mpe_A3189 twitching motility protein.
 
 0.831
Lcho_4069
PAS/PAC sensor hybrid histidine kinase; KEGG: azo:azo2482 putative hybrid sensor and regulator; TIGRFAM: PAS sensor protein; PFAM: response regulator receiver; ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS fold-3 domain protein; PAS fold-4 domain protein; PAS fold domain protein; SMART: PAS domain containing protein; PAC repeat-containing protein.
 
 
0.813
Lcho_2746
PFAM: response regulator receiver; KEGG: dac:Daci_1873 response regulator receiver protein.
 
 
 0.805
Lcho_0734
PFAM: response regulator receiver; KEGG: dac:Daci_0738 response regulator receiver protein.
 
 
 0.794
Your Current Organism:
Leptothrix cholodnii
NCBI taxonomy Id: 395495
Other names: L. cholodnii SP-6, Leptothrix cholodnii SP-6, Leptothrix cholodnii str. SP-6, Leptothrix cholodnii strain SP-6
Server load: low (12%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.