STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Lcho_0274Protease Do; KEGG: dac:Daci_1594 protease Do; TIGRFAM: protease Do; PFAM: peptidase S1 and S6 chymotrypsin/Hap; PDZ/DHR/GLGF domain protein; Belongs to the peptidase S1C family. (509 aa)    
Predicted Functional Partners:
Lcho_0666
PFAM: PDZ/DHR/GLGF domain protein; KEGG: mpt:Mpe_A1129 putative serine protease.
  
  
  0.936
Lcho_0602
Protease Do; KEGG: mpt:Mpe_A0645 subfamily S1C unassigned peptidase; TIGRFAM: protease Do; PFAM: peptidase S1 and S6 chymotrypsin/Hap; PDZ/DHR/GLGF domain protein; Belongs to the peptidase S1C family.
  
  
 
0.912
Lcho_0275
Histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; histidine kinase A domain protein; KEGG: azo:azo3673 two-component system histidine kinase.
    0.657
Lcho_0604
PFAM: Anti sigma-E protein RseA family protein; KEGG: mpt:Mpe_A0643 putative transmembrane sigma-E factor negative regulatory transcription regulator protein.
  
 
 0.573
Lcho_0273
PFAM: transglutaminase domain protein; transglutaminase domain protein; KEGG: rru:Rru_A1847 transglutaminase-like.
       0.566
Lcho_2843
TIGRFAM: membrane-associated zinc metalloprotease; PFAM: PDZ/DHR/GLGF domain protein; peptidase M50; KEGG: mpt:Mpe_A1972 hypothetical protein.
 
  
 0.504
rplI
Ribosomal protein L9; Binds to the 23S rRNA.
 
 
   0.492
Lcho_0640
KEGG: sde:Sde_2125 4-alpha-L-fucosyltransferase.
   
 0.477
glpK
Glycerol kinase; Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate; Belongs to the FGGY kinase family.
   
 0.477
Lcho_0277
Two component transcriptional regulator, winged helix family; PFAM: response regulator receiver; transcriptional regulator domain protein; KEGG: bte:BTH_I0673 DNA-binding response regulator.
  
  
 0.458
Your Current Organism:
Leptothrix cholodnii
NCBI taxonomy Id: 395495
Other names: L. cholodnii SP-6, Leptothrix cholodnii SP-6, Leptothrix cholodnii str. SP-6, Leptothrix cholodnii strain SP-6
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.