STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Lcho_0420PFAM: CBS domain containing protein; KEGG: pna:Pnap_1409 putative signal-transduction protein with CBS domains. (158 aa)    
Predicted Functional Partners:
guaA
GMP synthase, large subunit; Catalyzes the synthesis of GMP from XMP.
  
 
 0.770
purL
Phosphoribosylformylglycinamidine synthase; Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate.
  
  
 0.657
Lcho_0422
Adenosylhomocysteine nucleosidase; PFAM: purine or other phosphorylase family 1; KEGG: mpt:Mpe_A3574 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase.
     
 0.575
Lcho_0421
PFAM: Pirin domain protein; KEGG: mpt:Mpe_A0588 putative pirin-like protein; Belongs to the pirin family.
       0.570
htpG
Heat shock protein Hsp90; Molecular chaperone. Has ATPase activity.
   
 0.563
Lcho_0989
ABC transporter-related protein; PFAM: inner-membrane translocator; ABC transporter related; SMART: AAA ATPase; KEGG: pna:Pnap_0802 ABC transporter related; Belongs to the binding-protein-dependent transport system permease family.
  
    0.554
Lcho_2934
TIGRFAM: riboflavin biosynthesis protein RibD; PFAM: CMP/dCMP deaminase zinc-binding; bifunctional deaminase-reductase domain protein; KEGG: mpt:Mpe_A2945 bifunctional protein diaminohydroxyphosphoribosylaminopyrimidine deaminase, 5-amino-6-(5-phosphoribosylamino)uracil reductase.
  
  
 0.532
Lcho_1648
TIGRFAM: dihydrolipoamide dehydrogenase; PFAM: biotin/lipoyl attachment domain-containing protein; FAD-dependent pyridine nucleotide-disulphide oxidoreductase; pyridine nucleotide-disulphide oxidoreductase dimerisation region; KEGG: ajs:Ajs_2096 dihydrolipoamide dehydrogenase.
  
 
 0.530
Lcho_0423
Hypothetical protein; KEGG: mpt:Mpe_A3573 putative proline-rich protein.
       0.521
aroA
3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate; Belongs to the cytidylate kinase family. Type 1 subfamily.
 
  
 0.519
Your Current Organism:
Leptothrix cholodnii
NCBI taxonomy Id: 395495
Other names: L. cholodnii SP-6, Leptothrix cholodnii SP-6, Leptothrix cholodnii str. SP-6, Leptothrix cholodnii strain SP-6
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.