STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Lcho_0425NAD(P)(+) transhydrogenase (AB-specific); The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane; Belongs to the PNT beta subunit family. (474 aa)    
Predicted Functional Partners:
Lcho_0426
KEGG: mpt:Mpe_A3570 NAD(P) transhydrogenase, subunit alpha part 2.
 0.999
Lcho_0427
NAD(P)(+) transhydrogenase (AB-specific); PFAM: alanine dehydrogenase/PNT domain protein; KEGG: pna:Pnap_3800 NAD(P)(+) transhydrogenase (AB-specific).
 0.999
nadE
NAD+ synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
     
 0.938
nadK
ATP-NAD/AcoX kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
     
 0.909
nadD
Nicotinate (nicotinamide) nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).
     
 0.905
cobB
PFAM: Silent information regulator protein Sir2; KEGG: ajs:Ajs_2262 silent information regulator protein Sir2; Belongs to the sirtuin family. Class III subfamily.
    
  0.901
nudJ
PFAM: NUDIX hydrolase; KEGG: mpt:Mpe_A3567 hypothetical protein; Belongs to the Nudix hydrolase family. NudJ subfamily.
       0.602
Lcho_0424
PFAM: AMP-dependent synthetase and ligase; KEGG: mpt:Mpe_A3572 putative long-chain-fatty-acid--CoA ligase protein.
       0.471
Lcho_0422
Adenosylhomocysteine nucleosidase; PFAM: purine or other phosphorylase family 1; KEGG: mpt:Mpe_A3574 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase.
       0.469
Lcho_0423
Hypothetical protein; KEGG: mpt:Mpe_A3573 putative proline-rich protein.
       0.404
Your Current Organism:
Leptothrix cholodnii
NCBI taxonomy Id: 395495
Other names: L. cholodnii SP-6, Leptothrix cholodnii SP-6, Leptothrix cholodnii str. SP-6, Leptothrix cholodnii strain SP-6
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