STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Lcho_0433PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase; KEGG: pna:Pnap_1119 glyoxalase/bleomycin resistance protein/dioxygenase. (179 aa)    
Predicted Functional Partners:
Lcho_0434
KEGG: pna:Pnap_1120 4-hydroxyphenylpyruvate dioxygenase; TIGRFAM: 4-hydroxyphenylpyruvate dioxygenase; PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase.
 
   
 0.833
Lcho_0432
Fumarylacetoacetase; KEGG: pna:Pnap_1118 fumarylacetoacetase; TIGRFAM: fumarylacetoacetase; PFAM: fumarylacetoacetate (FAA) hydrolase; Domain of unknown function DUF1969.
     
 0.785
Lcho_0435
PFAM: transferase hexapeptide repeat containing protein; KEGG: rme:Rmet_1059 transferase hexapeptide repeat.
  
    0.641
Lcho_0436
PFAM: conserved hypothetical protein; KEGG: dac:Daci_3139 hypothetical protein.
       0.619
icmF
methylmalonyl-CoA mutase, large subunit; Catalyzes the reversible interconversion of isobutyryl-CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly.
  
  
 0.531
Lcho_0437
PFAM: L-carnitine dehydratase/bile acid-inducible protein F; KEGG: pna:Pnap_1122 L-carnitine dehydratase/bile acid-inducible protein F; Belongs to the CoA-transferase III family.
  
    0.503
Lcho_3661
TIGRFAM: benzoyl-CoA oxygenase/reductase, BoxA protein; PFAM: oxidoreductase FAD/NAD(P)-binding domain protein; 4Fe-4S ferredoxin iron-sulfur binding domain protein; KEGG: pna:Pnap_2942 oxidoreductase FAD/NAD(P)-binding domain protein.
  
  
 0.493
nuoD
NADH dehydrogenase I, D subunit; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; Belongs to the complex I 49 kDa subunit family.
  
  
 0.448
Lcho_2706
TIGRFAM: succinate dehydrogenase, cytochrome b556 subunit; PFAM: succinate dehydrogenase cytochrome b subunit; KEGG: mpt:Mpe_A2170 putative succinate dehydrogenase cytochrome b-556 subunit.
   
  
 0.447
nuoI
NADH-quinone oxidoreductase, chain I; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
  
  
 0.429
Your Current Organism:
Leptothrix cholodnii
NCBI taxonomy Id: 395495
Other names: L. cholodnii SP-6, Leptothrix cholodnii SP-6, Leptothrix cholodnii str. SP-6, Leptothrix cholodnii strain SP-6
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