STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Lcho_0499Histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; histidine kinase A domain protein; Two-component sensor kinase domain protein; KEGG: mpt:Mpe_A0077 putative transmembrane sensor histidine kinase transcription regulator protein. (518 aa)    
Predicted Functional Partners:
Lcho_2570
Two component transcriptional regulator, winged helix family; PFAM: response regulator receiver; transcriptional regulator domain protein; KEGG: pol:Bpro_2008 two component transcriptional regulator, winged helix family.
 
 0.980
Lcho_0498
Two component transcriptional regulator, winged helix family; PFAM: response regulator receiver; transcriptional regulator domain protein; KEGG: mpt:Mpe_A0076 response regulator transcription regulatory protein.
 
 
 0.936
Lcho_2571
Histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; histidine kinase A domain protein; Two-component sensor kinase domain protein; KEGG: pna:Pnap_1232 integral membrane sensor signal transduction histidine kinase.
  
  
 
0.922
Lcho_1696
Histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; histidine kinase A domain protein; Two-component sensor kinase domain protein; KEGG: rfr:Rfer_1092 periplasmic sensor signal transduction histidine kinase.
  
  
 
0.917
Lcho_3011
Two component transcriptional regulator, winged helix family; PFAM: response regulator receiver; transcriptional regulator domain protein; KEGG: rfr:Rfer_0503 two component transcriptional regulator, winged helix family.
 
 
 0.805
Lcho_1697
Two component transcriptional regulator, winged helix family; PFAM: response regulator receiver; transcriptional regulator domain protein; KEGG: dar:Daro_0429 response regulator receiver:transcriptional regulatory protein, C-terminal.
 
 
 0.800
Lcho_2624
Two component transcriptional regulator, winged helix family; PFAM: response regulator receiver; transcriptional regulator domain protein; KEGG: pna:Pnap_1535 two component transcriptional regulator, winged helix family.
 
 
 0.798
Lcho_0277
Two component transcriptional regulator, winged helix family; PFAM: response regulator receiver; transcriptional regulator domain protein; KEGG: bte:BTH_I0673 DNA-binding response regulator.
 
 
 0.796
Lcho_4069
PAS/PAC sensor hybrid histidine kinase; KEGG: azo:azo2482 putative hybrid sensor and regulator; TIGRFAM: PAS sensor protein; PFAM: response regulator receiver; ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS fold-3 domain protein; PAS fold-4 domain protein; PAS fold domain protein; SMART: PAS domain containing protein; PAC repeat-containing protein.
 
 
0.788
Lcho_2502
Multi-sensor hybrid histidine kinase; KEGG: dar:Daro_2754 PAS; TIGRFAM: PAS sensor protein; PFAM: response regulator receiver; ATP-binding region ATPase domain protein; histidine kinase A domain protein; Hpt domain protein; PAS fold-4 domain protein; PAS fold domain protein; SMART: PAS domain containing protein.
 
 
0.729
Your Current Organism:
Leptothrix cholodnii
NCBI taxonomy Id: 395495
Other names: L. cholodnii SP-6, Leptothrix cholodnii SP-6, Leptothrix cholodnii str. SP-6, Leptothrix cholodnii strain SP-6
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.