STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
zapDProtein of unknown function DUF1342; Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity. (251 aa)    
Predicted Functional Partners:
coaE
dephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family.
 
    0.968
ftsZ
Cell division protein FtsZ; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
    
 
 0.806
Lcho_2841
PFAM: outer membrane chaperone Skp (OmpH); KEGG: mpt:Mpe_A1970 putative transmembrane protein; Belongs to the skp family.
  
     0.719
yacG
Protein of unknown function DUF329; Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C- terminal domain of GyrB, which probably disrupts DNA binding by the gyrase.
       0.717
Lcho_2059
PFAM: protein of unknown function UPF0125; KEGG: mpt:Mpe_A1618 hypothetical protein; Belongs to the UPF0125 (RnfH) family.
  
     0.698
Lcho_0548
Peptidase A24A domain protein; Cleaves type-4 fimbrial leader sequence and methylates the N- terminal (generally Phe) residue.
  
    0.687
Lcho_4002
KEGG: mpt:Mpe_A0273 hypothetical protein.
  
     0.660
smg
PFAM: protein of unknown function DUF494; KEGG: mpt:Mpe_A0280 hypothetical protein; Belongs to the Smg family.
  
     0.659
Lcho_1971
KEGG: pol:Bpro_2280 hypothetical protein.
  
     0.642
Lcho_4015
PFAM: NUDIX hydrolase; KEGG: mpt:Mpe_A1071 putative dATP pyrophosphohydrolase.
  
     0.608
Your Current Organism:
Leptothrix cholodnii
NCBI taxonomy Id: 395495
Other names: L. cholodnii SP-6, Leptothrix cholodnii SP-6, Leptothrix cholodnii str. SP-6, Leptothrix cholodnii strain SP-6
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.