STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
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Gene Fusion
Cooccurrence
Coexpression
Experiments
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Textmining
[Homology]
Score
ureGUrease accessory protein UreG; Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG. (214 aa)    
Predicted Functional Partners:
ureF
Urease accessory protein UreF; Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.
 
 
 0.986
ureE
UreE urease accessory domain protein; Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly. Belongs to the UreE family.
 
 
 0.953
ureC
KEGG: mpt:Mpe_A0667 urease subunit alpha; TIGRFAM: urease, alpha subunit; PFAM: amidohydrolase; Urease alpha-subunit domain protein; Amidohydrolase 3; Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family.
 
  
 0.935
ureA
KEGG: pol:Bpro_1352 urease subunit gamma; TIGRFAM: urease, gamma subunit; PFAM: Urease gamma subunit region; Belongs to the urease gamma subunit family.
 
  
 0.933
ureD
Urease accessory protein UreD; Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.
 
 
 0.933
ureB
KEGG: pol:Bpro_1351 urease subunit beta; TIGRFAM: urease, beta subunit; PFAM: Urease beta subunit; Belongs to the urease beta subunit family.
 
  
 0.914
hypA
Hydrogenase nickel insertion protein HypA; Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.
  
 
 0.691
Lcho_2448
TIGRFAM: hydrogenase expression/formation protein HypD; PFAM: hydrogenase formation HypD protein; KEGG: mpt:Mpe_A2812 HypD' protein; Belongs to the HypD family.
  
  
 0.663
Lcho_2447
TIGRFAM: hydrogenase assembly chaperone hypC/hupF; PFAM: hydrogenase expression/formation protein (HUPF/HYPC); KEGG: rme:Rmet_1283 hydrogenase assembly chaperone HypC/HupF.
  
  
 0.658
Lcho_2643
KEGG: mpt:Mpe_A2569 putative FkbP-type peptidyl-prolyl cis-trans isomerase.
    
 
 0.571
Your Current Organism:
Leptothrix cholodnii
NCBI taxonomy Id: 395495
Other names: L. cholodnii SP-6, Leptothrix cholodnii SP-6, Leptothrix cholodnii str. SP-6, Leptothrix cholodnii strain SP-6
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