STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Lcho_0785KEGG: bxe:Bxe_C0462 putative DNA relaxase/nickase, TraS/VirD2-like. (321 aa)    
Predicted Functional Partners:
recB
Exodeoxyribonuclease V, beta subunit; A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and re [...]
  
 
 0.869
recC
Exodeoxyribonuclease V, gamma subunit; A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and r [...]
  
 
 0.840
Lcho_0866
PFAM: VirB8 family protein; KEGG: mpt:Mpe_A1681 type IV secretory pathway, VirB8 component.
 
     0.759
Lcho_0784
Hypothetical protein.
       0.727
Lcho_0002
DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]
  
 
 0.717
Lcho_0868
PFAM: TrbL/VirB6 plasmid conjugal transfer protein; KEGG: bxe:Bxe_A2654 putative type IV secretion system protein VirB6/TraH.
 
     0.693
Lcho_0870
TIGRFAM: type IV secretion/conjugal transfer ATPase, VirB4 family; PFAM: CagE TrbE VirB component of type IV transporter system; KEGG: bxe:Bxe_C0450 putative type IV secretion system protein VirB4/TraE.
 
   
 0.689
Lcho_0864
PFAM: conjugation TrbI family protein; KEGG: mpt:Mpe_A1679 type IV secretory pathway, VirB10 component.
 
     0.683
Lcho_0865
PFAM: Conjugal transfer protein TrbG/VirB9/CagX; KEGG: mpt:Mpe_A1680 type IV secretory pathway, VirB9 component.
 
     0.683
Lcho_0867
PFAM: type IV secretion system family protein; KEGG: bxe:Bxe_C0452 putative type IV secretion system protein VirB5/TraF.
 
     0.683
Your Current Organism:
Leptothrix cholodnii
NCBI taxonomy Id: 395495
Other names: L. cholodnii SP-6, Leptothrix cholodnii SP-6, Leptothrix cholodnii str. SP-6, Leptothrix cholodnii strain SP-6
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.