STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Lcho_0910PFAM: metallophosphoesterase; KEGG: mpt:Mpe_A3031 putative serine/threonine phosphatase. (247 aa)    
Predicted Functional Partners:
Lcho_0911
PFAM: UspA domain protein; SMART: tyrosine protein kinase; serine/threonine protein kinase; KEGG: mpt:Mpe_A3032 putative serine/threonine kinase.
 
   
 0.942
Lcho_0704
Non-canonical purine NTP pyrophosphatase, rdgB/HAM1 family; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family.
  
  
 0.849
Lcho_0149
PFAM: Ankyrin; KEGG: pol:Bpro_4103 ankyrin.
    
 
 0.783
Lcho_0909
PFAM: MltA-interacting MipA family protein; KEGG: mpt:Mpe_A1330 putative outer membrane protein.
       0.511
Lcho_3256
S-formylglutathione hydrolase; Serine hydrolase involved in the detoxification of formaldehyde.
  
  
 0.502
Lcho_0258
Peroxiredoxin; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.
   
 
 0.474
Lcho_1835
Heavy metal translocating P-type ATPase; TIGRFAM: ATPase, P-type (transporting), HAD superfamily, subfamily IC; copper-translocating P-type ATPase; heavy metal translocating P-type ATPase; PFAM: Haloacid dehalogenase domain protein hydrolase; Heavy metal transport/detoxification protein; E1-E2 ATPase-associated domain protein; KEGG: mpt:Mpe_A1640 P1 ATPase/HMA domain.
     
 0.405
Your Current Organism:
Leptothrix cholodnii
NCBI taxonomy Id: 395495
Other names: L. cholodnii SP-6, Leptothrix cholodnii SP-6, Leptothrix cholodnii str. SP-6, Leptothrix cholodnii strain SP-6
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