STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Lcho_0966KEGG: mpt:Mpe_A2246 hypothetical protein. (106 aa)    
Predicted Functional Partners:
lapB
Conserved hypothetical protein; Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane; Belongs to the LapB family.
 
   
 0.858
Lcho_0767
PFAM: HemY domain protein; KEGG: mpt:Mpe_A2999 putative porphyrin biosynthesis-related protein.
  
     0.718
Lcho_4234
PFAM: VanZ family protein; KEGG: mpt:Mpe_A0308 hypothetical protein.
  
     0.705
ftsL
Cell division protein FtsL; Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic.
  
     0.702
Lcho_1337
PFAM: cytochrome c class I; KEGG: rfr:Rfer_4077 cytochrome c, class I.
  
     0.686
lptE
Rare lipoprotein B; Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane; Belongs to the LptE lipoprotein family.
  
     0.682
Lcho_2710
KEGG: mpt:Mpe_A1366 putative signal peptide protein.
  
     0.667
Lcho_3370
PFAM: Rieske [2Fe-2S] domain protein; KEGG: aav:Aave_2012 Rieske (2Fe-2S) domain protein.
  
     0.667
Lcho_2513
ZipA FtsZ-binding region; Essential cell division protein that stabilizes the FtsZ protofilaments by cross-linking them and that serves as a cytoplasmic membrane anchor for the Z ring. Also required for the recruitment to the septal ring of downstream cell division proteins. Belongs to the ZipA family.
  
     0.654
Lcho_0766
PFAM: protein of unknown function DUF513 hemX; KEGG: mpt:Mpe_A3000 putative uroporphyrin-III methylase.
  
     0.651
Your Current Organism:
Leptothrix cholodnii
NCBI taxonomy Id: 395495
Other names: L. cholodnii SP-6, Leptothrix cholodnii SP-6, Leptothrix cholodnii str. SP-6, Leptothrix cholodnii strain SP-6
Server load: low (20%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.