STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Lcho_1003Putative metal dependent phosphohydrolase; KEGG: mpt:Mpe_A2795 hypothetical protein. (423 aa)    
Predicted Functional Partners:
Lcho_1002
KEGG: ajs:Ajs_0032 methyltransferase type 12.
 
     0.625
Lcho_4175
Response regulator receiver modulated diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(s); KEGG: eba:ebA6472 putative response regulator receiver; TIGRFAM: PAS sensor protein; diguanylate cyclase; PFAM: GGDEF domain containing protein; EAL domain protein; response regulator receiver; GAF domain protein; PAS fold-3 domain protein; PAS fold-4 domain protein; PAS fold domain protein; SMART: PAS domain containing protein.
 
  
 0.578
Lcho_3797
PFAM: Sulfate transporter/antisigma-factor antagonist STAS; KEGG: rfr:Rfer_0900 anti-sigma-factor antagonist (STAS) domain protein.
  
 
   0.517
Lcho_2508
KEGG: mpt:Mpe_A1948 hypothetical protein.
  
    0.495
flhC-2
Flagellar transcriptional activator FlhC; Functions in complex with FlhD as a master transcriptional regulator that regulates transcription of several flagellar and non- flagellar operons by binding to their promoter region. Activates expression of class 2 flagellar genes, including fliA, which is a flagellum-specific sigma factor that turns on the class 3 genes. Also regulates genes whose products function in a variety of physiological pathways; Belongs to the FlhC family.
       0.477
Lcho_0998
Chemotaxis phosphatase, CheZ; Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P).
 
     0.449
Lcho_2944
Metal dependent phosphohydrolase; KEGG: mpt:Mpe_A2511 conserved hypothetical HD-GYP hydrolase domain containing protein; TIGRFAM: metal dependent phophohydrolase; PFAM: metal-dependent phosphohydrolase HD sub domain; SMART: metal-dependent phosphohydrolase HD region.
  
     0.447
Lcho_0282
PFAM: metal-dependent phosphohydrolase HD sub domain; SMART: metal-dependent phosphohydrolase HD region; KEGG: pmy:Pmen_0570 metal dependent phosphohydrolase.
  
     0.433
Lcho_2578
PFAM: response regulator receiver; Tetratricopeptide TPR_4; Tetratricopeptide TPR_2 repeat protein; KEGG: rfr:Rfer_1420 response regulator receiver domain protein.
  
     0.422
Your Current Organism:
Leptothrix cholodnii
NCBI taxonomy Id: 395495
Other names: L. cholodnii SP-6, Leptothrix cholodnii SP-6, Leptothrix cholodnii str. SP-6, Leptothrix cholodnii strain SP-6
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