STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
dnaQDNA polymerase III, epsilon subunit; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'- 5' exonuclease. (241 aa)    
Predicted Functional Partners:
Lcho_0002
DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]
 
 0.983
dnaX
DNA polymerase III, subunits gamma and tau; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.
  
 0.982
Lcho_0980
DNA polymerase III, alpha subunit; KEGG: mpt:Mpe_A2252 DNA-directed DNA polymerase; TIGRFAM: DNA polymerase III, alpha subunit; PFAM: PHP domain protein; nucleic acid binding OB-fold tRNA/helicase-type; DNA polymerase III alpha subunit; SMART: phosphoesterase PHP domain protein.
   
 0.968
Lcho_0481
TIGRFAM: DNA polymerase III, delta subunit; PFAM: DNA polymerase III delta; KEGG: mpt:Mpe_A0216 DNA polymerase III subunit delta.
    
 0.952
Lcho_0238
KEGG: rfr:Rfer_3777 DNA polymerase III, epsilon subunit; TIGRFAM: DNA polymerase III, epsilon subunit; PFAM: Exonuclease RNase T and DNA polymerase III; SMART: Exonuclease.
 
 
0.928
Lcho_2594
PFAM: DNA polymerase III chi subunit HolC; KEGG: ajs:Ajs_1922 DNA polymerase III chi subunit, HolC.
   
 0.928
Lcho_0024
DNA polymerase III, epsilon subunit; KEGG: mpt:Mpe_A0049 DNA-directed DNA polymerase; TIGRFAM: DNA polymerase III, epsilon subunit; PFAM: Exonuclease RNase T and DNA polymerase III; SMART: Exonuclease.
  
  
 
0.921
Lcho_1879
TIGRFAM: DNA polymerase III, delta prime subunit; KEGG: mpt:Mpe_A1859 DNA-directed DNA polymerase.
   
 0.920
Lcho_2503
PFAM: Exonuclease RNase T and DNA polymerase III; SMART: Exonuclease; KEGG: pna:Pnap_0481 exonuclease, RNase T and DNA polymerase III.
     
  0.900
rnhA
Ribonuclease H; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
 
  
 0.897
Your Current Organism:
Leptothrix cholodnii
NCBI taxonomy Id: 395495
Other names: L. cholodnii SP-6, Leptothrix cholodnii SP-6, Leptothrix cholodnii str. SP-6, Leptothrix cholodnii strain SP-6
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