STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Lcho_1052TIGRFAM: quinone oxidoreductase, YhdH/YhfP family; PFAM: Alcohol dehydrogenase zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein; KEGG: mpt:Mpe_A0901 alcohol dehydrogenase. (327 aa)    
Predicted Functional Partners:
Lcho_2797
PFAM: phosphate acetyl/butaryl transferase; MaoC domain protein dehydratase; KEGG: rfr:Rfer_2974 bifunctional enoyl-CoA hydratase/phosphate acetyltransferase.
  
 0.925
Lcho_3332
TIGRFAM: methylmalonate-semialdehyde dehydrogenase; PFAM: Aldehyde Dehydrogenase_; KEGG: mpt:Mpe_A3524 putative transmembrane aldehyde dehydrogenase oxidoreductase protein.
   
 0.910
Lcho_2691
TIGRFAM: propionate--CoA ligase; PFAM: AMP-dependent synthetase and ligase; KEGG: rfr:Rfer_2322 propionate--CoA ligase.
  
 
 0.908
Lcho_4207
PFAM: acyl-CoA dehydrogenase domain protein; Acyl-CoA dehydrogenase type 2 domain; KEGG: rme:Rmet_0108 acyl-CoA dehydrogenase-like protein.
 
 0.908
Lcho_2461
PFAM: Enoyl-CoA hydratase/isomerase; KEGG: mag:amb2242 enoyl-CoA hydratase/carnithine racemase.
  
 0.907
acsA
acetate--CoA ligase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family.
   
 
 0.906
Lcho_2693
PFAM: biotin/lipoyl attachment domain-containing protein; Carbamoyl-phosphate synthase L chain ATP-binding; Carbamoyl-phosphate synthetase large chain domain protein; biotin carboxylase domain protein; KEGG: ajs:Ajs_2043 carbamoyl-phosphate synthase L chain, ATP-binding.
     
 0.904
Lcho_2694
PFAM: carboxyl transferase; KEGG: pol:Bpro_2164 carboxyl transferase.
     
 0.904
Lcho_2150
PFAM: pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; KEGG: rfr:Rfer_2186 pyruvate flavodoxin/ferredoxin oxidoreductase-like.
     
 0.902
Lcho_2151
PFAM: thiamine pyrophosphate protein domain protein TPP-binding; KEGG: rfr:Rfer_2185 thiamine pyrophosphate enzyme-like TPP-binding.
     
 0.901
Your Current Organism:
Leptothrix cholodnii
NCBI taxonomy Id: 395495
Other names: L. cholodnii SP-6, Leptothrix cholodnii SP-6, Leptothrix cholodnii str. SP-6, Leptothrix cholodnii strain SP-6
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