STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ureEUreE urease accessory domain protein; Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly. Belongs to the UreE family. (234 aa)    
Predicted Functional Partners:
ureF
Urease accessory protein UreF; Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.
  
 0.998
ureC
KEGG: mpt:Mpe_A0667 urease subunit alpha; TIGRFAM: urease, alpha subunit; PFAM: amidohydrolase; Urease alpha-subunit domain protein; Amidohydrolase 3; Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family.
 
  
 0.972
ureB
KEGG: pol:Bpro_1351 urease subunit beta; TIGRFAM: urease, beta subunit; PFAM: Urease beta subunit; Belongs to the urease beta subunit family.
 
  
 0.956
ureA
KEGG: pol:Bpro_1352 urease subunit gamma; TIGRFAM: urease, gamma subunit; PFAM: Urease gamma subunit region; Belongs to the urease gamma subunit family.
 
  
 0.956
ureG
Urease accessory protein UreG; Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG.
 
 
 0.953
ureD
Urease accessory protein UreD; Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.
 
  
 0.926
Lcho_2445
TIGRFAM: hydrogenase accessory protein HypB; PFAM: cobalamin synthesis protein P47K; KEGG: rme:Rmet_1285 hydrogenase accessory protein HypB.
  
 
 0.893
Lcho_1069
PFAM: protein of unknown function DUF894 DitE; major facilitator superfamily MFS_1; KEGG: pna:Pnap_1281 major facilitator superfamily MFS_1.
     
 0.704
Lcho_1085
TIGRFAM: urea ABC transporter, permease protein UrtB; PFAM: inner-membrane translocator; KEGG: pol:Bpro_1394 inner-membrane translocator; Belongs to the binding-protein-dependent transport system permease family.
 
   
 0.645
Lcho_1086
TIGRFAM: urea ABC transporter, permease protein UrtC; PFAM: inner-membrane translocator; KEGG: mpt:Mpe_A0699 putative permease transporter transmembrane protein; Belongs to the binding-protein-dependent transport system permease family.
 
   
 0.631
Your Current Organism:
Leptothrix cholodnii
NCBI taxonomy Id: 395495
Other names: L. cholodnii SP-6, Leptothrix cholodnii SP-6, Leptothrix cholodnii str. SP-6, Leptothrix cholodnii strain SP-6
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