STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ureAKEGG: pol:Bpro_1352 urease subunit gamma; TIGRFAM: urease, gamma subunit; PFAM: Urease gamma subunit region; Belongs to the urease gamma subunit family. (100 aa)    
Predicted Functional Partners:
ureC
KEGG: mpt:Mpe_A0667 urease subunit alpha; TIGRFAM: urease, alpha subunit; PFAM: amidohydrolase; Urease alpha-subunit domain protein; Amidohydrolase 3; Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family.
 0.999
ureB
KEGG: pol:Bpro_1351 urease subunit beta; TIGRFAM: urease, beta subunit; PFAM: Urease beta subunit; Belongs to the urease beta subunit family.
 0.999
ureF
Urease accessory protein UreF; Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.
 
 
 0.974
ureE
UreE urease accessory domain protein; Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly. Belongs to the UreE family.
 
  
 0.956
ureD
Urease accessory protein UreD; Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.
 
 
 0.953
ureG
Urease accessory protein UreG; Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG.
 
  
 0.933
Lcho_2098
Arginase; TIGRFAM: arginase; PFAM: Arginase/agmatinase/formiminoglutamase; KEGG: mpt:Mpe_A1081 arginase; Belongs to the arginase family.
    
  0.909
Lcho_3031
TIGRFAM: allophanate hydrolase; PFAM: Amidase; KEGG: mpt:Mpe_A0773 UreA amidolyase.
     
  0.900
Lcho_2445
TIGRFAM: hydrogenase accessory protein HypB; PFAM: cobalamin synthesis protein P47K; KEGG: rme:Rmet_1285 hydrogenase accessory protein HypB.
  
  
 0.694
Lcho_1078
Hypothetical protein.
       0.610
Your Current Organism:
Leptothrix cholodnii
NCBI taxonomy Id: 395495
Other names: L. cholodnii SP-6, Leptothrix cholodnii SP-6, Leptothrix cholodnii str. SP-6, Leptothrix cholodnii strain SP-6
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.