STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Lcho_1090Hypothetical protein; KEGG: mfa:Mfla_0451 alkaline phosphatase. (223 aa)    
Predicted Functional Partners:
secA
Preprotein translocase, SecA subunit; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane. Belongs to the SecA family.
    
 
 0.680
secB
Protein-export protein SecB; One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA.
    
 
 0.650
tig
Trigger factor; Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase; Belongs to the FKBP-type PPIase family. Tig subfamily.
    
 
 0.649
Lcho_4359
PFAM: OmpA/MotB domain protein; KEGG: pmy:Pmen_2437 OmpA/MotB domain protein.
  
  
 0.493
Lcho_1652
PFAM: protein of unknown function DUF839; KEGG: pol:Bpro_1725 twin-arginine translocation pathway signal.
  
  
 0.452
Lcho_2111
PFAM: protein of unknown function DUF839; KEGG: mpt:Mpe_A3526 hypothetical protein.
  
  
 0.452
Lcho_0946
Alkaline phosphatase; KEGG: mpt:Mpe_A3516 phosphodiesterase/alkaline phosphatase D.
  
  
 0.451
Lcho_3609
KEGG: pna:Pnap_1209 alkaline phosphatase.
  
  
 0.451
Lcho_0348
TIGRFAM: DNA protecting protein DprA; PFAM: SMF family protein; KEGG: mpt:Mpe_A0281 putative smf protein.
  
    0.450
phnC
ABC transporter-related protein; Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Phosphonates importer (TC 3.A.1.9.1) family.
   
  
 0.447
Your Current Organism:
Leptothrix cholodnii
NCBI taxonomy Id: 395495
Other names: L. cholodnii SP-6, Leptothrix cholodnii SP-6, Leptothrix cholodnii str. SP-6, Leptothrix cholodnii strain SP-6
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.