node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Lcho_0023 | Lcho_3289 | Lcho_0023 | Lcho_3289 | PFAM: NADP oxidoreductase coenzyme F420-dependent; KEGG: rso:RS01781 hypothetical protein. | PFAM: Ketopantoate hydroxymethyltransferase; KEGG: smd:Smed_5004 ketopantoate hydroxymethyltransferase. | 0.416 |
Lcho_0023 | panB | Lcho_0023 | Lcho_1178 | PFAM: NADP oxidoreductase coenzyme F420-dependent; KEGG: rso:RS01781 hypothetical protein. | 3-methyl-2-oxobutanoate hydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family. | 0.568 |
Lcho_0023 | panC | Lcho_0023 | Lcho_1177 | PFAM: NADP oxidoreductase coenzyme F420-dependent; KEGG: rso:RS01781 hypothetical protein. | Pantoate--beta-alanine ligase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family. | 0.877 |
Lcho_0023 | panD | Lcho_0023 | Lcho_2657 | PFAM: NADP oxidoreductase coenzyme F420-dependent; KEGG: rso:RS01781 hypothetical protein. | Aspartate 1-decarboxylase; Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine. | 0.462 |
Lcho_0153 | Lcho_3289 | Lcho_0153 | Lcho_3289 | KEGG: aav:Aave_0260 2-dehydropantoate 2-reductase; TIGRFAM: 2-dehydropantoate 2-reductase; PFAM: Ketopantoate reductase ApbA/PanE domain protein. | PFAM: Ketopantoate hydroxymethyltransferase; KEGG: smd:Smed_5004 ketopantoate hydroxymethyltransferase. | 0.921 |
Lcho_0153 | panB | Lcho_0153 | Lcho_1178 | KEGG: aav:Aave_0260 2-dehydropantoate 2-reductase; TIGRFAM: 2-dehydropantoate 2-reductase; PFAM: Ketopantoate reductase ApbA/PanE domain protein. | 3-methyl-2-oxobutanoate hydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family. | 0.921 |
Lcho_0153 | panC | Lcho_0153 | Lcho_1177 | KEGG: aav:Aave_0260 2-dehydropantoate 2-reductase; TIGRFAM: 2-dehydropantoate 2-reductase; PFAM: Ketopantoate reductase ApbA/PanE domain protein. | Pantoate--beta-alanine ligase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family. | 0.943 |
Lcho_0153 | panD | Lcho_0153 | Lcho_2657 | KEGG: aav:Aave_0260 2-dehydropantoate 2-reductase; TIGRFAM: 2-dehydropantoate 2-reductase; PFAM: Ketopantoate reductase ApbA/PanE domain protein. | Aspartate 1-decarboxylase; Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine. | 0.415 |
Lcho_1909 | panB | Lcho_1909 | Lcho_1178 | KEGG: pau:PA14_58700 nicotinate-nucleotide pyrophosphorylase; TIGRFAM: nicotinate-nucleotide pyrophosphorylase; PFAM: Quinolinate phosphoribosyl transferase; Belongs to the NadC/ModD family. | 3-methyl-2-oxobutanoate hydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family. | 0.699 |
Lcho_1909 | panC | Lcho_1909 | Lcho_1177 | KEGG: pau:PA14_58700 nicotinate-nucleotide pyrophosphorylase; TIGRFAM: nicotinate-nucleotide pyrophosphorylase; PFAM: Quinolinate phosphoribosyl transferase; Belongs to the NadC/ModD family. | Pantoate--beta-alanine ligase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family. | 0.624 |
Lcho_3289 | Lcho_0023 | Lcho_3289 | Lcho_0023 | PFAM: Ketopantoate hydroxymethyltransferase; KEGG: smd:Smed_5004 ketopantoate hydroxymethyltransferase. | PFAM: NADP oxidoreductase coenzyme F420-dependent; KEGG: rso:RS01781 hypothetical protein. | 0.416 |
Lcho_3289 | Lcho_0153 | Lcho_3289 | Lcho_0153 | PFAM: Ketopantoate hydroxymethyltransferase; KEGG: smd:Smed_5004 ketopantoate hydroxymethyltransferase. | KEGG: aav:Aave_0260 2-dehydropantoate 2-reductase; TIGRFAM: 2-dehydropantoate 2-reductase; PFAM: Ketopantoate reductase ApbA/PanE domain protein. | 0.921 |
Lcho_3289 | gcvP | Lcho_3289 | Lcho_1559 | PFAM: Ketopantoate hydroxymethyltransferase; KEGG: smd:Smed_5004 ketopantoate hydroxymethyltransferase. | Glycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | 0.569 |
Lcho_3289 | guaA | Lcho_3289 | Lcho_2063 | PFAM: Ketopantoate hydroxymethyltransferase; KEGG: smd:Smed_5004 ketopantoate hydroxymethyltransferase. | GMP synthase, large subunit; Catalyzes the synthesis of GMP from XMP. | 0.553 |
Lcho_3289 | ilvD | Lcho_3289 | Lcho_1490 | PFAM: Ketopantoate hydroxymethyltransferase; KEGG: smd:Smed_5004 ketopantoate hydroxymethyltransferase. | KEGG: mpt:Mpe_A1387 dihydroxy-acid dehydratase; TIGRFAM: dihydroxy-acid dehydratase; PFAM: dihydroxy-acid and 6-phosphogluconate dehydratase; Belongs to the IlvD/Edd family. | 0.910 |
Lcho_3289 | ilvE | Lcho_3289 | Lcho_1301 | PFAM: Ketopantoate hydroxymethyltransferase; KEGG: smd:Smed_5004 ketopantoate hydroxymethyltransferase. | Branched-chain amino acid aminotransferase; Acts on leucine, isoleucine and valine. Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. | 0.915 |
Lcho_3289 | panB | Lcho_3289 | Lcho_1178 | PFAM: Ketopantoate hydroxymethyltransferase; KEGG: smd:Smed_5004 ketopantoate hydroxymethyltransferase. | 3-methyl-2-oxobutanoate hydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family. | 0.928 |
Lcho_3289 | panC | Lcho_3289 | Lcho_1177 | PFAM: Ketopantoate hydroxymethyltransferase; KEGG: smd:Smed_5004 ketopantoate hydroxymethyltransferase. | Pantoate--beta-alanine ligase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family. | 0.964 |
Lcho_3289 | panD | Lcho_3289 | Lcho_2657 | PFAM: Ketopantoate hydroxymethyltransferase; KEGG: smd:Smed_5004 ketopantoate hydroxymethyltransferase. | Aspartate 1-decarboxylase; Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine. | 0.934 |
gcvP | Lcho_3289 | Lcho_1559 | Lcho_3289 | Glycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | PFAM: Ketopantoate hydroxymethyltransferase; KEGG: smd:Smed_5004 ketopantoate hydroxymethyltransferase. | 0.569 |