STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Lcho_1543PFAM: Sporulation domain protein; KEGG: mca:MCA2191 hypothetical protein. (834 aa)    
Predicted Functional Partners:
ccmA
Heme exporter protein CcmA; Part of the ABC transporter complex CcmAB involved in the biogenesis of c-type cytochromes; once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. CcmA exporter (TC 3.A.1.107) family.
       0.779
Lcho_1545
Heme exporter protein CcmB; Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes; Belongs to the CcmB/CycW/HelB family.
       0.779
Lcho_1542
TIGRFAM: cytochrome C family protein; KEGG: aba:Acid345_0471 hypothetical protein.
   
   0.616
Lcho_1541
KEGG: mca:MCA2189 cytochrome c family protein.
   
   0.585
Lcho_2563
PFAM: Forkhead-associated protein; adenylyl cyclase class-3/4/guanylyl cyclase; KEGG: mpt:Mpe_A2492 adenylate cyclase family 3-like protein.
  
  
 0.516
ccmC
Heme exporter protein CcmC; Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes; Belongs to the CcmC/CycZ/HelC family.
       0.453
Lcho_1547
Hypothetical protein; Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes; Belongs to the CcmD/CycX/HelD family.
       0.438
Lcho_0191
FHA domain containing protein; PFAM: Forkhead-associated protein; KEGG: mpt:Mpe_A0067 hypothetical protein.
  
  
 0.428
Lcho_1019
KEGG: mpt:Mpe_A0568 flagellar biosynthesis ATPase; TIGRFAM: ATPase, FliI/YscN family; flagellar protein export ATPase FliI; PFAM: H+transporting two-sector ATPase alpha/beta subunit central region; SMART: AAA ATPase.
  
 
 0.428
Lcho_1540
KEGG: aba:Acid345_0468 hypothetical protein.
       0.407
Your Current Organism:
Leptothrix cholodnii
NCBI taxonomy Id: 395495
Other names: L. cholodnii SP-6, Leptothrix cholodnii SP-6, Leptothrix cholodnii str. SP-6, Leptothrix cholodnii strain SP-6
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