| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| Lcho_1609 | hisE | Lcho_1609 | Lcho_1610 | PFAM: histidine triad (HIT) protein; KEGG: mpt:Mpe_A0840 hypothetical protein. | TIGRFAM: phosphoribosyl-ATP diphosphatase; PFAM: phosphoribosyl-ATP pyrophosphohydrolase; KEGG: mpt:Mpe_A0838 phosphoribosyl-ATP pyrophosphatase. | 0.765 |
| Lcho_1609 | tatA | Lcho_1609 | Lcho_1608 | PFAM: histidine triad (HIT) protein; KEGG: mpt:Mpe_A0840 hypothetical protein. | Twin-arginine translocation protein, TatA/E family subunit; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system. | 0.693 |
| Lcho_1609 | tatB | Lcho_1609 | Lcho_1607 | PFAM: histidine triad (HIT) protein; KEGG: mpt:Mpe_A0840 hypothetical protein. | Twin-arginine translocation protein, TatB subunit; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation. | 0.648 |
| Lcho_1609 | tatC | Lcho_1609 | Lcho_1606 | PFAM: histidine triad (HIT) protein; KEGG: mpt:Mpe_A0840 hypothetical protein. | Sec-independent protein translocase, TatC subunit; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides. | 0.467 |
| Lcho_1881 | tatA | Lcho_1881 | Lcho_1608 | TIGRFAM: hydrolase, TatD family; PFAM: TatD-related deoxyribonuclease; KEGG: mpt:Mpe_A1857 putative deoxyribonuclease. | Twin-arginine translocation protein, TatA/E family subunit; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system. | 0.454 |
| Lcho_1881 | tatB | Lcho_1881 | Lcho_1607 | TIGRFAM: hydrolase, TatD family; PFAM: TatD-related deoxyribonuclease; KEGG: mpt:Mpe_A1857 putative deoxyribonuclease. | Twin-arginine translocation protein, TatB subunit; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation. | 0.454 |
| Lcho_1881 | tatC | Lcho_1881 | Lcho_1606 | TIGRFAM: hydrolase, TatD family; PFAM: TatD-related deoxyribonuclease; KEGG: mpt:Mpe_A1857 putative deoxyribonuclease. | Sec-independent protein translocase, TatC subunit; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides. | 0.451 |
| groL | icmF | Lcho_0483 | Lcho_3844 | Chaperonin GroEL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. | methylmalonyl-CoA mutase, large subunit; Catalyzes the reversible interconversion of isobutyryl-CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly. | 0.441 |
| groL | tatC | Lcho_0483 | Lcho_1606 | Chaperonin GroEL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. | Sec-independent protein translocase, TatC subunit; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides. | 0.453 |
| groL | yajC | Lcho_0483 | Lcho_0343 | Chaperonin GroEL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. | Preprotein translocase, YajC subunit; The SecYEG-SecDF-YajC-YidC holo-translocon (HTL) protein secretase/insertase is a supercomplex required for protein secretion, insertion of proteins into membranes, and assembly of membrane protein complexes. While the SecYEG complex is essential for assembly of a number of proteins and complexes, the SecDF-YajC-YidC subcomplex facilitates these functions. | 0.457 |
| hisE | Lcho_1609 | Lcho_1610 | Lcho_1609 | TIGRFAM: phosphoribosyl-ATP diphosphatase; PFAM: phosphoribosyl-ATP pyrophosphohydrolase; KEGG: mpt:Mpe_A0838 phosphoribosyl-ATP pyrophosphatase. | PFAM: histidine triad (HIT) protein; KEGG: mpt:Mpe_A0840 hypothetical protein. | 0.765 |
| hisE | tatA | Lcho_1610 | Lcho_1608 | TIGRFAM: phosphoribosyl-ATP diphosphatase; PFAM: phosphoribosyl-ATP pyrophosphohydrolase; KEGG: mpt:Mpe_A0838 phosphoribosyl-ATP pyrophosphatase. | Twin-arginine translocation protein, TatA/E family subunit; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system. | 0.785 |
| hisE | tatB | Lcho_1610 | Lcho_1607 | TIGRFAM: phosphoribosyl-ATP diphosphatase; PFAM: phosphoribosyl-ATP pyrophosphohydrolase; KEGG: mpt:Mpe_A0838 phosphoribosyl-ATP pyrophosphatase. | Twin-arginine translocation protein, TatB subunit; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation. | 0.667 |
| hisE | tatC | Lcho_1610 | Lcho_1606 | TIGRFAM: phosphoribosyl-ATP diphosphatase; PFAM: phosphoribosyl-ATP pyrophosphohydrolase; KEGG: mpt:Mpe_A0838 phosphoribosyl-ATP pyrophosphatase. | Sec-independent protein translocase, TatC subunit; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides. | 0.445 |
| icmF | groL | Lcho_3844 | Lcho_0483 | methylmalonyl-CoA mutase, large subunit; Catalyzes the reversible interconversion of isobutyryl-CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly. | Chaperonin GroEL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. | 0.441 |
| icmF | tatC | Lcho_3844 | Lcho_1606 | methylmalonyl-CoA mutase, large subunit; Catalyzes the reversible interconversion of isobutyryl-CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly. | Sec-independent protein translocase, TatC subunit; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides. | 0.459 |
| secD | secF | Lcho_0344 | Lcho_0345 | Protein-export membrane protein SecD; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA. | Protein-export membrane protein SecF; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA. | 0.999 |
| secD | tatA | Lcho_0344 | Lcho_1608 | Protein-export membrane protein SecD; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA. | Twin-arginine translocation protein, TatA/E family subunit; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system. | 0.457 |
| secD | tatB | Lcho_0344 | Lcho_1607 | Protein-export membrane protein SecD; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA. | Twin-arginine translocation protein, TatB subunit; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation. | 0.438 |
| secD | tatC | Lcho_0344 | Lcho_1606 | Protein-export membrane protein SecD; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA. | Sec-independent protein translocase, TatC subunit; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides. | 0.456 |