STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
fliARNA polymerase, sigma 28 subunit, FliA/WhiG; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor controls the expression of flagella-related genes; Belongs to the sigma-70 factor family. FliA subfamily. (238 aa)    
Predicted Functional Partners:
Lcho_2736
PFAM: Anti-sigma-28 factor FlgM family protein; KEGG: mpt:Mpe_A3075 negative regulator of flagellin synthesis (anti-S28 factor).
  
 0.990
Lcho_2725
TIGRFAM: flagellar hook-associated protein FlgK; PFAM: protein of unknown function DUF1078 domain protein; KEGG: mpt:Mpe_A3064 flagellar hook-associated protein.
 
  
 0.954
Lcho_2734
Flagellar basal-body rod protein FlgB; Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body.
 
 
 0.948
Lcho_2733
TIGRFAM: flagellar basal-body rod protein FlgC; PFAM: flagellar basal body rod protein; protein of unknown function DUF1078 domain protein; KEGG: mpt:Mpe_A3072 flagellar basal body rod protein; Belongs to the flagella basal body rod proteins family.
 
 
 0.934
Lcho_2732
Flagellar hook capping protein; Required for flagellar hook formation. May act as a scaffolding protein.
 
  
 0.927
Lcho_1327
Putative RNA polymerase, sigma 28 subunit, FliA/WhiG family; TIGRFAM: RNA polymerase sigma factor, sigma-70 family; PFAM: sigma-70 region 4 domain protein; KEGG: bpt:Bpet2096 flagellar-specific RNA polymerase sigma factor.
  
  
 
0.926
flhA
Flagellar biosynthesis protein FlhA; Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin; Belongs to the FHIPEP (flagella/HR/invasion proteins export pore) family.
 
  
 0.923
Lcho_2730
TIGRFAM: flagellar basal-body rod protein FlgF; PFAM: flagellar basal body rod protein; KEGG: mpt:Mpe_A3069 flagellar basal body and hook protein; Belongs to the flagella basal body rod proteins family.
 
  
 0.918
Lcho_2731
PFAM: flagellar basal body rod protein; protein of unknown function DUF1078 domain protein; flagellar basal body FlaE domain protein; KEGG: bxe:Bxe_A0143 putative flagellar hook protein FlgE.
 
  
 0.917
Lcho_1023
PFAM: surface presentation of antigens (SPOA) protein; flagellar motor switch protein FliM; KEGG: mpt:Mpe_A0572 flagellar motor switch protein.
 
 
 0.916
Your Current Organism:
Leptothrix cholodnii
NCBI taxonomy Id: 395495
Other names: L. cholodnii SP-6, Leptothrix cholodnii SP-6, Leptothrix cholodnii str. SP-6, Leptothrix cholodnii strain SP-6
Server load: low (22%) [HD]