STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
metZO-succinylhomoserine sulfhydrylase; Catalyzes the formation of L-homocysteine from O-succinyl-L- homoserine (OSHS) and hydrogen sulfide. (413 aa)    
Predicted Functional Partners:
Lcho_3398
TIGRFAM: cysteine synthase; cysteine synthase A; PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; KEGG: mpt:Mpe_A0450 cysteine synthase; Belongs to the cysteine synthase/cystathionine beta- synthase family.
 
 0.968
Lcho_3268
PFAM: homocysteine S-methyltransferase; KEGG: mpt:Mpe_A0166 5-methyltetrahydrofolate--homocysteine S-methyltransferase.
  
 
 0.951
metXS
Homoserine O-acetyltransferase; Transfers a succinyl group from succinyl-CoA to L-homoserine, forming succinyl-L-homoserine.
 
  
 0.943
Lcho_2784
PFAM: nitrite/sulfite reductase hemoprotein beta-component ferrodoxin domain protein; nitrite and sulphite reductase 4Fe-4S region; KEGG: mpt:Mpe_A1503 putative nitrite/sulfite reductase.
  
 0.936
Lcho_4276
KEGG: eba:ebA6307 O-acetylhomoserine sulfhydrylase, gene: MetY; TIGRFAM: O-acetylhomoserine/O-acetylserine sulfhydrylase; PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent protein; DegT/DnrJ/EryC1/StrS aminotransferase; aromatic amino acid beta-eliminating lyase/threonine aldolase.
 
 
0.933
Lcho_1522
O-acetylhomoserine/O-acetylserine sulfhydrylase; KEGG: aav:Aave_2997 transcriptional regulator, fis family; TIGRFAM: O-acetylhomoserine/O-acetylserine sulfhydrylase; PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent protein.
 
 
0.930
Lcho_3270
Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
  
 
 0.930
ahcY
Adenosylhomocysteinase; May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.
  
 0.924
Lcho_2056
PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent protein; KEGG: mpt:Mpe_A1615 putative cystathionine beta-lyase.
  
  
 
0.924
Lcho_1707
TIGRFAM: pyridine nucleotide-disulfide oxidoreductase family protein; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; KEGG: rsh:Rsph17029_3291 FAD-dependent pyridine nucleotide-disulphide oxidoreductase.
   
 0.914
Your Current Organism:
Leptothrix cholodnii
NCBI taxonomy Id: 395495
Other names: L. cholodnii SP-6, Leptothrix cholodnii SP-6, Leptothrix cholodnii str. SP-6, Leptothrix cholodnii strain SP-6
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