STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Lcho_1807PFAM: WD-40 repeat protein; KEGG: amr:AM1_4989 WD-repeat protein. (1214 aa)    
Predicted Functional Partners:
Lcho_2486
PFAM: beta-lactamase domain protein; RNA-metabolising metallo-beta-lactamase; KEGG: tbd:Tbd_0095 metallo-beta-lactamase superfamily protein.
    
 0.972
alaS
alanyl-tRNA synthetase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
   
 0.962
Lcho_0149
PFAM: Ankyrin; KEGG: pol:Bpro_4103 ankyrin.
   
 0.922
Lcho_2793
PFAM: Dual specificity protein phosphatase; SMART: Protein-tyrosine phosphatase, catalytic; KEGG: rpe:RPE_4503 ADP-ribosylation/crystallin J1.
   
 0.917
Lcho_2384
Bis(5'-nucleosyl)-tetraphosphatase (symmetrical); Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP; Belongs to the Ap4A hydrolase family.
   
 0.894
Lcho_2736
PFAM: Anti-sigma-28 factor FlgM family protein; KEGG: mpt:Mpe_A3075 negative regulator of flagellin synthesis (anti-S28 factor).
  
 
 0.882
rpoZ
DNA-directed RNA polymerase, omega subunit; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
   
 0.863
rpoA
DNA-directed RNA polymerase, alpha subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
   
 0.863
rpoB
DNA-directed RNA polymerase, beta subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
   
 0.858
Lcho_0186
PFAM: RNP-1 like RNA-binding protein; KEGG: mpt:Mpe_A3805 RNA-binding region RNP-1.
    
 0.842
Your Current Organism:
Leptothrix cholodnii
NCBI taxonomy Id: 395495
Other names: L. cholodnii SP-6, Leptothrix cholodnii SP-6, Leptothrix cholodnii str. SP-6, Leptothrix cholodnii strain SP-6
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.