STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Lcho_2003TIGRFAM: succinic semialdehyde dehydrogenase; PFAM: Aldehyde Dehydrogenase_; KEGG: mpt:Mpe_A2324 succinate-semialdehyde dehydrogenase (NAD(P)+); Belongs to the aldehyde dehydrogenase family. (496 aa)    
Predicted Functional Partners:
Lcho_2002
TIGRFAM: 4-aminobutyrate aminotransferase; PFAM: aminotransferase class-III; KEGG: pna:Pnap_2630 4-aminobutyrate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
 
 0.971
Lcho_2704
KEGG: mpt:Mpe_A2168 succinate dehydrogenase; TIGRFAM: succinate dehydrogenase, flavoprotein subunit; succinate dehydrogenase or fumarate reductase, flavoprotein subunit; PFAM: fumarate reductase/succinate dehydrogenase flavoprotein domain protein; FAD-dependent pyridine nucleotide-disulphide oxidoreductase; Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.
   
 0.921
Lcho_2703
TIGRFAM: succinate dehydrogenase and fumarate reductase iron-sulfur protein; KEGG: mpt:Mpe_A2167 succinate dehydrogenase (ubiquinone).
   
 
 0.913
Lcho_0856
PFAM: Aldehyde Dehydrogenase_; KEGG: pol:Bpro_0086 aldehyde dehydrogenase.
  
  
 
0.909
Lcho_1122
PFAM: HpcH/HpaI aldolase; KEGG: mpt:Mpe_A0974 2-dehydro-3-deoxyglucarate aldolase; Belongs to the HpcH/HpaI aldolase family.
  
 
 0.908
Lcho_2705
TIGRFAM: succinate dehydrogenase, hydrophobic membrane anchor protein; KEGG: mpt:Mpe_A2169 transmembrane succinate dehydrogenase (hydrophobic membrane anchor subunit) oxidoreductase protein.
   
 
 0.905
Lcho_2706
TIGRFAM: succinate dehydrogenase, cytochrome b556 subunit; PFAM: succinate dehydrogenase cytochrome b subunit; KEGG: mpt:Mpe_A2170 putative succinate dehydrogenase cytochrome b-556 subunit.
   
 
  0.904
Lcho_2701
KEGG: mpt:Mpe_A2165 type II citrate synthase; TIGRFAM: citrate synthase I; PFAM: Citrate synthase; Belongs to the citrate synthase family.
  
 0.882
Lcho_3065
Hydro-lyase, Fe-S type, tartrate/fumarate subfamily, alpha subunit; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family.
   
 
 0.831
Lcho_2884
2-oxoglutarate dehydrogenase, E1 subunit; KEGG: mpt:Mpe_A2013 alpha-ketoglutarate decarboxylase; TIGRFAM: 2-oxoglutarate dehydrogenase, E1 subunit; PFAM: dehydrogenase E1 component; Transketolase central region.
   
 
 0.826
Your Current Organism:
Leptothrix cholodnii
NCBI taxonomy Id: 395495
Other names: L. cholodnii SP-6, Leptothrix cholodnii SP-6, Leptothrix cholodnii str. SP-6, Leptothrix cholodnii strain SP-6
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