STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Lcho_2012PFAM: major facilitator superfamily MFS_1; KEGG: ajs:Ajs_0039 major facilitator superfamily MFS_1. (421 aa)    
Predicted Functional Partners:
Lcho_2011
Redoxin domain protein; PFAM: alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen; Redoxin domain protein; KEGG: cte:CT1072 thiol:disulfide interchange protein DsbE, putative.
       0.664
dsbD
Protein-disulfide reductase; Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps. Belongs to the thioredoxin family. DsbD subfamily.
       0.630
Lcho_2305
PFAM: protein of unknown function DUF1468; KEGG: mpt:Mpe_A3057 hypothetical protein.
  
     0.595
Lcho_2009
Regulator of ribonuclease activity A; Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions.
       0.553
Lcho_3496
KEGG: mpt:Mpe_A3231 hypothetical protein.
  
     0.549
Lcho_3433
Transcriptional regulator, Crp/Fnr family; PFAM: cyclic nucleotide-binding; regulatory protein Crp; KEGG: pol:Bpro_0605 transcriptional regulator, Crp/Fnr family.
  
     0.519
Lcho_2013
KEGG: mpt:Mpe_A1550 hypothetical protein.
       0.482
Lcho_0346
KEGG: mpt:Mpe_A0279 hypothetical protein.
  
   
 0.412
Lcho_2568
KEGG: pna:Pnap_1235 hypothetical protein.
  
     0.411
Lcho_0084
KEGG: aav:Aave_3831 restriction endonuclease.
  
     0.409
Your Current Organism:
Leptothrix cholodnii
NCBI taxonomy Id: 395495
Other names: L. cholodnii SP-6, Leptothrix cholodnii SP-6, Leptothrix cholodnii str. SP-6, Leptothrix cholodnii strain SP-6
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.