STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Lcho_21235-oxoprolinase (ATP-hydrolyzing); PFAM: Hydantoinase/oxoprolinase; Hydantoinase B/oxoprolinase; Hydantoinaseoxoprolinase domain protein; KEGG: mpt:Mpe_A2968 5-oxoprolinase (ATP-hydrolyzing). (1245 aa)    
Predicted Functional Partners:
Lcho_2560
Gamma-glutamyltransferase; PFAM: gamma-glutamyltranspeptidase; KEGG: ajs:Ajs_1042 gamma-glutamyltransferase.
 
  
 0.929
Lcho_2920
ChaC family protein; Catalyzes the cleavage of glutathione into 5-oxo-L-proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides; Belongs to the gamma-glutamylcyclotransferase family.
  
  
 0.922
Lcho_4355
Gamma-glutamyltransferase; PFAM: gamma-glutamyltranspeptidase; KEGG: tth:TTC0403 gamma-glutamyltranspeptidase.
    
 0.918
Lcho_3940
TIGRFAM: glutamate--cysteine ligase; PFAM: glutamate--cysteine ligase GshA; KEGG: mpt:Mpe_A0173 putative glutamate--cysteine ligase.
    
  0.903
gshA
TIGRFAM: glutamate--cysteine ligase; KEGG: pol:Bpro_3399 glutamate--cysteine ligase, monofunctional; Belongs to the glutamate--cysteine ligase type 1 family. Type 1 subfamily.
     
  0.900
Lcho_3225
Glutamate--cysteine ligase GCS2; ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity; Belongs to the glutamate--cysteine ligase type 2 family. YbdK subfamily.
     
  0.900
Lcho_3396
PFAM: glutamine amidotransferase class-II; glutamate synthase alpha subunit domain protein; ferredoxin-dependent glutamate synthase; glutamate synthase; KEGG: mpt:Mpe_A3103 glutamate synthase (ferredoxin).
    
 0.862
Lcho_1626
PFAM: Glu/Leu/Phe/Val dehydrogenase; Glu/Leu/Phe/Val dehydrogenase dimerisation region; KEGG: mpt:Mpe_A3745 putative glutamic dehyrogenase; Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
    
 0.854
Lcho_1628
Delta-1-pyrroline-5-carboxylate dehydrogenase; Oxidizes proline to glutamate for use as a carbon and nitrogen source; In the C-terminal section; belongs to the aldehyde dehydrogenase family.
    
  0.842
Lcho_2684
PFAM: NAD-glutamate dehydrogenase; KEGG: pol:Bpro_3020 NAD-glutamate dehydrogenase.
 
  
  0.828
Your Current Organism:
Leptothrix cholodnii
NCBI taxonomy Id: 395495
Other names: L. cholodnii SP-6, Leptothrix cholodnii SP-6, Leptothrix cholodnii str. SP-6, Leptothrix cholodnii strain SP-6
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.