STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Lcho_2133PFAM: Radical SAM domain protein; Radical SAM domain protein; SMART: Elongator protein 3/MiaB/NifB; KEGG: aav:Aave_2437 radical SAM N-terminal domain protein. (810 aa)    
Predicted Functional Partners:
Lcho_3364
Putative sigma54 specific transcriptional regulator; PFAM: sigma-54 factor interaction domain-containing protein; helix-turn-helix Fis-type; 4-vinyl reductase 4VR; Activator of aromatic catabolism; ATPase associated with various cellular activities AAA_5; SMART: AAA ATPase; KEGG: ajs:Ajs_0205 sigma54 specific transcriptional regulator, fis family.
  
  
 0.895
Lcho_2134
KEGG: mpt:Mpe_A1301 hypothetical protein.
       0.462
Lcho_2217
PFAM: protein of unknown function DUF344; KEGG: reh:H16_A1212 hypothetical protein.
   
    0.457
Lcho_3677
PFAM: protein of unknown function DUF344; KEGG: xac:XAC0941 transcriptional regulator.
   
    0.457
Lcho_4264
PFAM: protein of unknown function DUF344; KEGG: mpt:Mpe_A1572 hypothetical protein.
   
    0.457
Lcho_0703
Oxygen-independent coproporphyrinogen III oxidase; Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine. Belongs to the anaerobic coproporphyrinogen-III oxidase family.
  
  
 0.416
Lcho_2771
KEGG: mpt:Mpe_A2470 coproporphyrinogen III oxidase; TIGRFAM: oxygen-independent coproporphyrinogen III oxidase; PFAM: Radical SAM domain protein; HemN domain protein; SMART: Elongator protein 3/MiaB/NifB; Belongs to the anaerobic coproporphyrinogen-III oxidase family.
  
  
 0.416
Your Current Organism:
Leptothrix cholodnii
NCBI taxonomy Id: 395495
Other names: L. cholodnii SP-6, Leptothrix cholodnii SP-6, Leptothrix cholodnii str. SP-6, Leptothrix cholodnii strain SP-6
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